Protein: ZN445
Zinc finger protein 445 (ZFP445) (Zinc finger protein 168) (Zinc finger protein with KRAB and SCAN domains 15)

Gene: ZN445, ZNF445
Organism: Homo sapiens
Interactions: 61
UniProt ID: P59923

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding
GO:0010385 - double-stranded methylated DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

600543

ZSC20
Zinc finger and SCAN domain-containing protein 20

3

11

High-throughput

0.861

High

948216

ZN707
Zinc finger protein 707

3

11

High-throughput

0.861

High

948219

ZN396
Zinc finger protein 396

3

20

High-throughput

0.861

High

171857

ZN263
Zinc finger protein 263

2

10

High-throughput

0.811

High

948198

ZN169
Zinc finger protein 169

2

6

High-throughput

0.811

High

948208

Z324B
Zinc finger protein 324B

2

7

High-throughput

0.811

High

948213

ZN483
Zinc finger protein 483

2

3

High-throughput

0.811

High

948229

ZN232
Zinc finger protein 232

2

19

High-throughput

0.811

High

517745

GLI4
Zinc finger protein GLI4

1

14

High-throughput

0.691

High

948193

ZN543
Zinc finger protein 543

1

3

High-throughput

0.691

High

948197

ZN460
Zinc finger protein 460

1

5

High-throughput

0.691

High

948201

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

1

15

High-throughput

0.691

High

948204

ZSC23
Zinc finger and SCAN domain-containing protein 23

1

20

High-throughput

0.691

High

948209

ZN467
Zinc finger protein 467

1

10

High-throughput

0.691

High

948223

ZN287
Zinc finger protein 287

1

5

High-throughput

0.691

High

948224

ZNF71
Endothelial zinc finger protein induced by tumor necrosis factor alpha

1

5

High-throughput

0.691

High

948227

ZBT47
Zinc finger and BTB domain-containing protein 47

1

13

High-throughput

0.691

High

948195

TIF1B
Transcription intermediary factor 1-beta

4

20

High-throughput

0.691

High

948221

NDEL1
Nuclear distribution protein nudE-like 1

3

10

High-throughput

0.607

High

948220

SETB2
Histone-lysine N-methyltransferase SETDB2

2

0

High-throughput

0.602

High

948222

NXF2
Nuclear RNA export factor 2

2

0

High-throughput

0.602

High

855011

NOP2
28S rRNA

2

3

High-throughput

0.601

High

421822

A4
Amyloid-beta precursor protein

2

7

High-throughput

0.574

High

948202

CCDC6
Coiled-coil domain-containing protein 6

2

3

High-throughput

0.574

High

286914

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

10

High-throughput

0.536

High

615692

RL17
Large ribosomal subunit protein uL22

1

3

High-throughput

0.536

High

658060

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.536

High

853209

CBX5
Chromobox protein homolog 5

1

20

High-throughput

0.536

High

948190

PRR3
Proline-rich protein 3

1

1

High-throughput

0.536

High

948191

NOTC2
Neurogenic locus notch homolog protein 2

1

7

High-throughput

0.536

High

948192

SRSF4
Serine/arginine-rich splicing factor 4

1

7

High-throughput

0.536

High

948211

CUL9
Cullin-9

1

7

High-throughput

0.536

High

948215

TRI52
E3 ubiquitin-protein ligase TRIM52

1

7

High-throughput

0.536

High

948225

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

1

High-throughput

0.536

High

948228

PURG
Purine-rich element-binding protein gamma

1

8

High-throughput

0.536

High

343748

LDOC1
Protein LDOC1

1

0

High-throughput

0.513

High

948194

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.513

High

948203

SKDA1
SKI/DACH domain-containing protein 1

1

0

High-throughput

0.513

High

948212

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.513

High

859757

RL28
Large ribosomal subunit protein eL28

1

3

High-throughput

0.489

High

948200

OASL
2'-5'-oligoadenylate synthase-like protein

1

3

High-throughput

0.489

High

948205

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

2

High-throughput

0.489

High

948207

K1C40
Keratin, type I cytoskeletal 40

1

3

High-throughput

0.489

High

948217

MR1L1
MORF4 family-associated protein 1-like 1

1

1

High-throughput

0.489

High

948230

RL36
Large ribosomal subunit protein eL36

1

6

High-throughput

0.489

High

718093

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

3

High-throughput

0.479

High

809990

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.479

High

948196

CUL3
Cullin-3

1

20

High-throughput

0.479

High

596014

H12
Histone H1.2

1

4

High-throughput

0.445

High

717746

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

3

High-throughput

0.445

High

948199

NUMA1
Nuclear mitotic apparatus protein 1

1

4

High-throughput

0.445

High

214558

WDR62
WD repeat-containing protein 62

1

0

High-throughput

0.426

High

455736

H10
Histone H1.0

1

0

High-throughput

0.426

High

948189

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.426

High

948214

H1X
Histone H1.10

1

0

High-throughput

0.426

High

189137

IPO8
Importin-8

1

10

High-throughput

0.407

High

334731

IPO7
Importin-7

1

10

High-throughput

0.407

High

948210

SYT12
Synaptotagmin-12

2

0

High-throughput

0.328

High

948226

CCG5
Voltage-dependent calcium channel gamma-5 subunit

2

0

High-throughput

0.328

High

948218

LURA1
Leucine rich adaptor protein 1

1

0

High-throughput

0.279

Low

948206

SGO1
Shugoshin 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025