HitPredict

Interactor 1: A4PIV9 (A4PIV9)
Fusion protein SYT-SSX2
Gene: SYT-SSX2

Interactor 2: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23540691
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 488 Hs			1 1647
+	Hs
		60089 A4PIV7_HUMAN (1-488): 5.36e-84: 269: 97.34		SMCA4_HUMAN (1-1647): 0: 1105: 100.00
+	Hs
		846980 SSXT_HUMAN (1-411): 4.37e-61: 207: 99.76		SMCA4_HUMAN (1-1647): 0: 1105: 100.00
+	Mm
		1111934 SSXT_MOUSE (1-411): 4.47e-64: 215: 95.86		SMCA4_MOUSE (1-1647): 0: 1069: 96.66
+	Rn
		88986 D4ABC5_RAT (1-411): 9.79e-62: 209: 94.65		SMCA4_RAT (1-1647): 0: 1070: 96.60
+	Hs
		257459 CREST_HUMAN (1-411): 1.49e-38: 146: 54.99		SMCA4_HUMAN (1-1647): 0: 1105: 100.00
+	Mm
		1111948 CREST_MOUSE (1-411): 3.73e-43: 159: 56.69		SMCA4_MOUSE (1-1647): 0: 1069: 96.66
+	Hs
		60100 A4PIW0_HUMAN (1-488): 1.71e-74: 243: 93.65		SMCA2_HUMAN (1-1647): 0: 980: 71.69
+	Hs
		846783 SSXT_HUMAN (1-411): 4.37e-61: 207: 99.76		SMCA2_HUMAN (1-1647): 0: 980: 71.69
+	Mm
		1150290 CREST_MOUSE (1-411): 3.73e-43: 159: 56.69		SMCA2_MOUSE (40-1647): 0: 986: 72.73
+	Hs
		257458 CREST_HUMAN (1-411): 1.49e-38: 146: 54.99		SMCA2_HUMAN (1-1647): 0: 980: 71.69
+	Hs
		846785 SSX2_HUMAN (389-488): 2.56e-32: 123: 83.17		SMCA2_HUMAN (1-1647): 0: 980: 71.69
+	Hs
		60097 A4PIW0_HUMAN (1-488): 1.71e-74: 243: 93.65		SMCA5_HUMAN (626-1631): 0: 835: 27.41
+	Hs
		229409 SSXT_HUMAN (1-411): 4.37e-61: 207: 99.76		SMCA5_HUMAN (626-1631): 0: 835: 27.41
+	Hs
		229412 SSX2_HUMAN (389-488): 2.56e-32: 123: 83.17		SMCA5_HUMAN (626-1631): 0: 835: 27.41
+	Hs
		229378 BPTF_HUMAN (29-421): 9.77e-25: 110: 13.28		SMCA5_HUMAN (626-1631): 0: 835: 27.41
+	Hs
		658659 BPTF_HUMAN (29-421): 9.77e-25: 110: 13.28		SMCA1_HUMAN (639-1619): 0: 832: 28.82
+	Hs
		1017295 BPTF_HUMAN (29-421): 9.77e-25: 110: 13.28		CHD4_HUMAN (482-1630): 0: 722: 23.79
+	Hs
		1017327 BPTF_HUMAN (29-421): 9.77e-25: 110: 13.28		CHD5_HUMAN (448-1641): 0: 718: 22.29
+	Hs
		1017286 BPTF_HUMAN (29-421): 9.77e-25: 110: 13.28		CHD3_HUMAN (300-1646): 0: 711: 20.80
+	Hs
		123925 SPT5H_HUMAN (79-437): 1.23e-24: 110: 13.90		CHD3_HUMAN (300-1646): 0: 711: 20.80