Protein: PALS2
Protein PALS2 (MAGUK p55 subfamily member 6) (Membrane protein, palmitoylated 6) (Veli-associated MAGUK 1) (VAM-1)

Gene: PALS2
Organism: Homo sapiens
Interactions: 79
UniProt ID: Q9NZW5

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0016020 - membrane
GO:0065003 - protein-containing complex assembly
GO:0070062 - extracellular exosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1450016

LIN7C
Protein lin-7 homolog C

6

20

High-throughput

0.944

High

167723

LIN7A
Protein lin-7 homolog A

4

20

Small-scale

0.897

High

1437597

LIN7B
Protein lin-7 homolog B

4

20

High-throughput

0.890

High

1122735

MPP2
MAGUK p55 subfamily member 2

3

18

High-throughput

0.839

High

1357046

S20A1
Sodium-dependent phosphate transporter 1

3

4

High-throughput

0.662

High

376032

RASK
GTPase KRas

1

20

High-throughput

0.618

High

463806

LYN
Tyrosine-protein kinase Lyn

1

13

High-throughput

0.618

High

710528

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

942931

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

9

High-throughput

0.618

High

733861

CDD
Cytidine deaminase

3

2

High-throughput

0.604

High

1066197

NSUN2
RNA cytosine C(5)-methyltransferase NSUN2

2

0

High-throughput

0.602

High

299587

TRIO
Triple functional domain protein

1

8

High-throughput

0.595

High

1453648

SNX9
Sorting nexin-9

1

0

High-throughput

0.589

High

171111

VP26C
Vacuolar protein sorting-associated protein 26C

1

0

High-throughput

0.584

High

1402975

CP2S1
Cytochrome P450 2S1

2

2

High-throughput

0.574

High

1255871

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.553

High

547493

DMD
Dystrophin

1

10

High-throughput

0.536

High

1134752

NUMA1
Nuclear mitotic apparatus protein 1

1

3

High-throughput

0.536

High

106763

APRIO
Alternative prion protein

2

6

High-throughput

0.533

High

95802

E5RI47
MAGUK p55 scaffold protein 2

1

17

High-throughput

0.514

High

626384

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

High-throughput

0.512

High

1405689

NECD
Necdin

1

2

High-throughput

0.512

High

186082

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

848736

MAGA9
Melanoma-associated antigen 9

1

2

High-throughput

0.489

High

884252

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.489

High

1181031

DB136
Defensin beta 136

1

1

High-throughput

0.489

High

1332119

EIF1A
Probable RNA-binding protein EIF1AD

1

2

High-throughput

0.489

High

1367910

THRSP
Thyroid hormone-inducible hepatic protein

1

1

High-throughput

0.489

High

1386612

OPTN
Optineurin

1

7

High-throughput

0.489

High

1453644

TRPS1
Zinc finger transcription factor Trps1

1

1

High-throughput

0.489

High

391504

FRIL
Ferritin light chain

1

1

High-throughput

0.481

High

896909

DYN2
Dynamin-2

1

1

High-throughput

0.481

High

954295

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.481

High

1032260

EXOSX
Exosome complex component 10

1

1

High-throughput

0.481

High

1324925

RHG18
Rho GTPase-activating protein 18

1

4

High-throughput

0.481

High

412720

NTRK1
High affinity nerve growth factor receptor

1

16

High-throughput

0.479

High

744468

SSR3
Somatostatin receptor type 3

1

14

Small-scale

0.479

High

767360

MERL
Merlin

1

20

High-throughput

0.479

High

1127305

KCJ12
ATP-sensitive inward rectifier potassium channel 12

1

20

Small-scale

0.479

High

1381982

CK052
Uncharacterized protein C11orf52

1

4

High-throughput

0.479

High

1431469

P2Y12
P2Y purinoceptor 12

1

15

High-throughput

0.479

High

1314262

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

1

3

High-throughput

0.470

High

903502

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

0

High-throughput

0.460

High

1446088

DLRB1
Dynein light chain roadblock-type 1

1

0

High-throughput

0.460

High

1453647

SKAP
Small kinetochore-associated protein

1

0

High-throughput

0.460

High

1334599

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

1433094

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

948951

CD81
CD81 antigen

1

1

High-throughput

0.445

High

1033954

SC6A3
Sodium-dependent dopamine transporter

1

8

High-throughput

0.445

High

1063080

S20A2
Sodium-dependent phosphate transporter 2

1

4

High-throughput

0.445

High

1209741

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

1280233

MILR1
Allergin-1

1

4

High-throughput

0.445

High

1398006

MF14A
Hippocampus abundant transcript 1 protein

1

2

High-throughput

0.445

High

838805

MTREX
Exosome RNA helicase MTR4

1

1

High-throughput

0.439

High

125643

LEG9
Galectin-9

1

1

High-throughput

0.437

High

243159

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.437

High

377761

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.437

High

887473

CEBPD
CCAAT/enhancer-binding protein delta

1

2

Small-scale

0.437

High

1067779

EP300
Histone acetyltransferase p300

1

3

High-throughput

0.437

High

1197729

MIDN
Midnolin

1

3

High-throughput

0.437

High

1453643

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

1389482

NTCP4
Sodium/bile acid cotransporter 4

1

0

High-throughput

0.426

High

1059985

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

4

Small-scale

0.408

High

1436445

MINY3
Ubiquitin carboxyl-terminal hydrolase MINDY-3

3

0

High-throughput

0.347

High

1413441

NAT9
Alpha/beta-tubulin-N-acetyltransferase 9

2

0

High-throughput

0.328

High

1279033

TAFA3
Chemokine-like protein TAFA-3

1

0

High-throughput

0.279

Low

1315257

CA174
UPF0688 protein C1orf174

1

0

High-throughput

0.279

Low

1449447

CENPM
Centromere protein M

1

0

High-throughput

0.279

Low

295247

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

0

High-throughput

0.251

Low

337402

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.251

Low

914971

THOP1
Thimet oligopeptidase

1

0

High-throughput

0.251

Low

1452245

AATF
Protein AATF

1

0

High-throughput

0.251

Low

294448

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

353593

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

1435383

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

1453646

LIPT
Lipoyl amidotransferase LIPT1, mitochondrial

1

0

High-throughput

0.249

Low

142431

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.232

Low

1104146

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1453645

PNMA2
Paraneoplastic antigen Ma2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025