HitPredict

Interactor 1: FGF7 (P21781)
Fibroblast growth factor 7 (FGF-7) (Heparin-binding growth factor 7) (HBGF-7) (Keratinocyte growth factor)
Gene: FGF7

Interactor 2: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 11714710, 7499435, 9582367, 10339576, 8663044, 11121055, 10950949, 1309608
Identification Methods pull down, affinity chromatography technology, cross-linking study, biochemical, saturation binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FGF~I-set, FGF~Ig_3
Common GO terms GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0008201 - heparin binding
GO:0008284 - positive regulation of cell population proliferation
and 8 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 194
Hs

1 821
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Mm
+ Xl
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024