Protein: NHP2
H/ACA ribonucleoprotein complex subunit 2 (Nucleolar protein family A member 2) (snoRNP protein NHP2)

Gene: NHP2
Organism: Homo sapiens
Interactions: 114
UniProt ID: Q9NX24

Gene Ontology (top 5):
GO:0000454 - snoRNA guided rRNA pseudouridine synthesis
GO:0000781 - chromosome, telomeric region
GO:0003723 - RNA binding
GO:0003730 - mRNA 3'-UTR binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1446297

NOP10
H/ACA ribonucleoprotein complex subunit 3

10

2

High-throughput

0.978

High

257982

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

4

4

Small-scale

0.892

High

1347161

WDR48
WD repeat-containing protein 48

1

9

High-throughput

0.691

High

1447817

DDX21
Nucleolar RNA helicase 2

1

7

High-throughput

0.691

High

1451697

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

2

3

Small-scale

0.624

High

854946

RECQ1
ATP-dependent DNA helicase Q1

1

4

High-throughput

0.618

High

1207451

HABP4
Intracellular hyaluronan-binding protein 4

1

3

High-throughput

0.618

High

1335000

SERB1
SERPINE1 mRNA-binding protein 1

1

3

High-throughput

0.618

High

1451700

NOL12
Nucleolar protein 12

1

1

High-throughput

0.618

High

1393416

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

1

Small-scale

0.611

High

1451694

GAR1
H/ACA ribonucleoprotein complex subunit 1

2

4

High-throughput

0.611

High

1451693

LYAR
Cell growth-regulating nucleolar protein

2

0

High-throughput

0.585

High

373302

MYC
Myc proto-oncogene protein

2

6

High-throughput

0.584

High

397067

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

1437367

LN28A
Protein lin-28 homolog A

2

8

High-throughput

0.571

High

1451704

NEMO
NF-kappa-B essential modulator

1

2

High-throughput

0.561

High

1227569

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.553

High

788236

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

833211

MNDA
Myeloid cell nuclear differentiation antigen

1

5

High-throughput

0.536

High

994837

YBOX1
Y-box-binding protein 1

1

7

High-throughput

0.536

High

1029769

FOXK2
Forkhead box protein K2

1

2

High-throughput

0.536

High

1099282

SRSF5
Serine/arginine-rich splicing factor 5

1

7

High-throughput

0.536

High

1099574

SRSF6
Serine/arginine-rich splicing factor 6

1

9

High-throughput

0.536

High

1291239

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.536

High

269812

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

2

1

High-throughput

0.526

High

925988

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.513

High

1180508

C19L2
CWF19-like protein 2

1

0

High-throughput

0.513

High

1270656

COX15
Heme A synthase COX15

1

0

High-throughput

0.513

High

1451158

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.513

High

1239681

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

2

High-throughput

0.508

High

861808

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

13

High-throughput

0.501

High

993777

UBC9
SUMO-conjugating enzyme UBC9

1

2

Small-scale

0.501

High

1400037

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

13

High-throughput

0.501

High

1411898

UTP23
rRNA-processing protein UTP23 homolog

1

2

Small-scale

0.501

High

534001

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

1

1

High-throughput

0.494

High

844032

HD
Huntingtin

1

0

High-throughput

0.493

High

389540

FINC
Fibronectin

1

2

High-throughput

0.489

High

129484

MEN1
Menin

1

2

High-throughput

0.479

High

134888

SAP18
Histone deacetylase complex subunit SAP18

1

1

High-throughput

0.479

High

173454

XPO1
Exportin-1

1

4

High-throughput

0.479

High

248110

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

284239

SRS10
Serine/arginine-rich splicing factor 10

1

4

High-throughput

0.479

High

326068

UBR5
E3 ubiquitin-protein ligase UBR5

1

10

High-throughput

0.479

High

331363

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.479

High

355605

NSD2
Histone-lysine N-methyltransferase NSD2

1

4

Small-scale

0.479

High

386297

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

Small-scale

0.479

High

404475

GCR
Glucocorticoid receptor

1

5

High-throughput

0.479

High

406722

MYCN
N-myc proto-oncogene protein

1

6

High-throughput

0.479

High

431260

LA
Lupus La protein

1

7

High-throughput

0.479

High

630056

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

765938

BMI1
Polycomb complex protein BMI-1

1

8

High-throughput

0.479

High

766899

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

786888

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

3

High-throughput

0.479

High

879534

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.479

High

913816

ZN131
Zinc finger protein 131

1

7

High-throughput

0.479

High

965277

WDR5
WD repeat-containing protein 5

1

8

High-throughput

0.479

High

980438

H4
Histone H4

1

2

High-throughput

0.479

High

988223

TRA2B
Transformer-2 protein homolog beta

1

6

High-throughput

0.479

High

998874

H31
Histone H3.1

1

2

High-throughput

0.479

High

1024881

VIGLN
Vigilin

1

3

High-throughput

0.479

High

1025760

PURA
Transcriptional activator protein Pur-alpha

1

1

High-throughput

0.479

High

1037412

H11
Histone H1.1

1

3

High-throughput

0.479

High

1085628

FOXO1
Forkhead box protein O1

1

3

High-throughput

0.479

High

1104687

IKZF1
DNA-binding protein Ikaros

1

3

High-throughput

0.479

High

1105105

TCOF
Treacle protein

1

1

Small-scale

0.479

High

1107271

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

1134551

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

1

Small-scale

0.479

High

1137548

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1138693

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1161711

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1252535

LN28B
Protein lin-28 homolog B

1

12

High-throughput

0.479

High

1275858

RM21
Large ribosomal subunit protein bL21m

1

1

High-throughput

0.479

High

1280553

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

13

High-throughput

0.479

High

1290770

ZCH18
Zinc finger CCCH domain-containing protein 18

1

3

High-throughput

0.479

High

1328976

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

3

High-throughput

0.479

High

1352789

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

1367418

ESR2
Estrogen receptor beta

1

5

High-throughput

0.479

High

1404797

RING2
E3 ubiquitin-protein ligase RING2

1

9

High-throughput

0.479

High

1420961

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

4

High-throughput

0.479

High

1438044

RC3H2
Roquin-2

1

5

High-throughput

0.479

High

1451696

RM27
Large ribosomal subunit protein bL27m

1

1

High-throughput

0.479

High

1451699

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1451701

IKZF3
Zinc finger protein Aiolos

1

3

High-throughput

0.479

High

872805

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

1048731

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1418266

RM04
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.458

High

1451695

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.458

High

1451698

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.458

High

1130490

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

1238133

HMBX1
Homeobox-containing protein 1

1

3

Small-scale

0.445

High

74066

MYO9A
Unconventional myosin-IXa

1

1

High-throughput

0.437

High

157917

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.437

High

401585

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.437

High

971179

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

1087695

M4K2
Mitogen-activated protein kinase kinase kinase kinase 2

1

3

High-throughput

0.437

High

1385885

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.437

High

1387979

RM38
Large ribosomal subunit protein mL38

1

1

High-throughput

0.437

High

1438961

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

1

2

High-throughput

0.437

High

1451285

PIHD1
PIH1 domain-containing protein 1

1

3

High-throughput

0.437

High

1451702

TRAF6
TNF receptor-associated factor 6

1

6

High-throughput

0.437

High

1451703

MAFB
Transcription factor MafB

1

2

High-throughput

0.437

High

1361844

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.282

High

441453

CHLE
Cholinesterase

1

0

High-throughput

0.279

Low

1394563

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.279

Low

106738

APRIO
Alternative prion protein

1

0

Small-scale

0.261

Low

404931

PRIO
Major prion protein

1

0

Small-scale

0.261

Low

882393

RM19
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.249

Low

1104137

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low

1280194

FBX33
F-box only protein 33

1

0

High-throughput

0.249

Low

1328312

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.249

Low

1338400

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1349566

RM30
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.249

Low

1430523

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.249

Low

1448960

RM17
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025