HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: FLOT2 (Q14254)
Flotillin-2 (Epidermal surface antigen) (ESA) (Membrane component chromosome 17 surface marker 1)
Gene: FLOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0031410 - cytoplasmic vesicle
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 821 Hs			1 428
+	Hs
		507997 FGFR1_HUMAN (1-820): 0: 772: 71.17		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		607967 FGFR4_HUMAN (22-810): 0: 684: 55.86		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		665397 EPHA3_HUMAN (18-778): 3.24e-168: 514: 18.30		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		872646 EPHA4_HUMAN (18-794): 4.37e-165: 506: 18.60		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		872442 EPHA5_HUMAN (18-766): 3.48e-163: 502: 17.53		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		674425 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		665237 EPHA2_HUMAN (18-798): 4.64e-157: 485: 19.21		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		968376 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		1052408 NTRK2_HUMAN (123-765): 4.81e-153: 469: 23.43		FLOT2_HUMAN (1-428): 5.86e-158: 454: 100.00
+	Hs
		508258 FGFR1_HUMAN (1-820): 0: 772: 71.17		STML2_HUMAN (26-220): 1.09e-16: 83: 19.90
+	Hs
		279447 EPHA2_HUMAN (18-798): 4.64e-157: 485: 19.21		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Hs
		279518 ROR2_HUMAN (11-820): 1.91e-156: 482: 20.29		FLOT1_HUMAN (5-417): 1.06e-121: 362: 47.49
+	Mm
		975165 EPHA2_MOUSE (18-798): 7.62e-160: 492: 18.84		PODO_MOUSE (4-219): 1.04e-24: 106: 15.74
+	Mm
		963048 UFO_MOUSE (4-818): 1.83e-159: 488: 22.46		PODO_MOUSE (4-219): 1.04e-24: 106: 15.74
+	Hs
		1354627 EPHA6_HUMAN (9-788): 5.01e-162: 499: 17.99		STML2_HUMAN (26-220): 1.09e-16: 83: 19.90
+	Hs
		385690 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		STML2_HUMAN (26-220): 1.09e-16: 83: 19.90
+	Hs
		729377 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		STML2_HUMAN (26-220): 1.09e-16: 83: 19.90