HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 821 Hs			1 2365
+	Hs
		508190 FGFR1_HUMAN (1-820): 0: 772: 71.17		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		608119 FGFR4_HUMAN (22-810): 0: 684: 55.86		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		601535 FGFR2_HUMAN (1-821): 0: 863: 100.00		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		1083890 NTRK2_HUMAN (123-765): 4.81e-153: 469: 23.43		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		254442 FGFR1_HUMAN (1-820): 0: 772: 71.17		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		508011 FGFR1_HUMAN (1-820): 0: 772: 71.17		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		507954 FGFR1_HUMAN (1-820): 0: 772: 71.17		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82
+	Hs
		665271 EPHA2_HUMAN (18-798): 4.64e-157: 485: 19.21		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		1083861 NTRK2_HUMAN (123-765): 4.81e-153: 469: 23.43		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		665375 EPHA3_HUMAN (18-778): 3.24e-168: 514: 18.30		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		254431 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		1189813 EPHA6_HUMAN (9-788): 5.01e-162: 499: 17.99		MYH14_HUMAN (2035-2363): 1.9e-15: 85.4: 15.06
+	Hs
		551614 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		665581 EPHB2_HUMAN (9-766): 1.95e-166: 511: 17.58		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82
+	Hs
		674470 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		MYH14_HUMAN (2035-2363): 1.9e-15: 85.4: 15.06
+	Hs
		972340 TIE2_HUMAN (7-763): 1.63e-155: 485: 22.83		MYH14_HUMAN (2035-2363): 1.9e-15: 85.4: 15.06
+	Hs
		384384 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		384385 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Hs
		384210 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		384666 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82