HitPredict

Interactor 1: FBRL (P22087)
rRNA 2'-O-methyltransferase fibrillarin (EC 2.1.1.-) (34 kDa nucleolar scleroderma antigen) (Histone-glutamine methyltransferase) (U6 snRNA 2'-O-methyltransferase fibrillarin)
Gene: FBL

Interactor 2: DCA13 (Q9NV06)
DDB1- and CUL4-associated factor 13 (WD repeat and SOF domain-containing protein 1)
Gene: DCAF13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	29499938, 30283081, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0032040 - small-subunit processome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 321 Hs			1 445
+	Sc
		549368 FBRL_YEAST (85-313): 1.1e-136: 392: 70.76		DCA13_YEAST (1-444): 1.03e-100: 310: 42.13
+	Hs
		603388 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		LIS1_HUMAN (4-184): 1.13e-42: 157: 15.87
+	Hs
		603422 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		WDR5_HUMAN (311-444): 1.54e-27: 114: 9.49
+	Hs
		603635 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		SNR40_HUMAN (312-439): 6.18e-23: 101: 8.33
+	Hs
		603471 FBRL_HUMAN (1-321): 1.98e-177: 495: 100.00		TBL3_HUMAN (289-436): 7.69e-11: 66.3: 5.13