Protein: ITA3
Integrin alpha-3 (CD49 antigen-like family member C) (FRP-2) (Galactoprotein B3) (GAPB3) (VLA-3 subunit alpha) (CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain; Integrin alpha-3 light chain]

Gene: ITA3, ITGA3
Organism: Homo sapiens
Interactions: 62
UniProt ID: P26006

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0001968 - fibronectin binding
GO:0002020 - protease binding
GO:0005178 - integrin binding
GO:0005518 - collagen binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

431712

ITB1
Integrin beta-1

4

20

Small-scale

0.886

High

127281

LEG8
Galectin-8

6

20

Small-scale

0.736

High

683588

CD151
CD151 antigen

5

20

Small-scale

0.714

High

641912

CD9
CD9 antigen

3

20

Small-scale

0.643

High

480711

LEG1
Galectin-1

2

20

High-throughput

0.621

High

592622

ITB4
Integrin beta-4

1

20

Small-scale

0.618

High

612037

ITB5
Integrin beta-5

1

20

Small-scale

0.618

High

563231

CFTR
Cystic fibrosis transmembrane conductance regulator

2

2

High-throughput

0.601

High

683601

FHL2
Four and a half LIM domains protein 2

1

10

Small-scale

0.586

High

683581

EPHA2
Ephrin type-A receptor 2

2

11

Small-scale

0.584

High

351661

SG1D1
Secretoglobin family 1D member 1

2

2

High-throughput

0.574

High

440380

FYN
Tyrosine-protein kinase Fyn

2

6

High-throughput

0.571

High

631064

RAB5A
Ras-related protein Rab-5A

2

6

High-throughput

0.571

High

683597

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

1

High-throughput

0.571

High

683606

ABI1
Abl interactor 1

2

5

High-throughput

0.571

High

683609

SH3K1
SH3 domain-containing kinase-binding protein 1

2

4

High-throughput

0.571

High

683610

SH3G3
Endophilin-A3

2

3

High-throughput

0.571

High

683582

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.547

High

351817

BY55
CD160 antigen

1

4

High-throughput

0.536

High

683583

PDIA3
Protein disulfide-isomerase A3

1

4

Small-scale

0.536

High

683612

FBX6
F-box only protein 6

2

11

High-throughput

0.533

High

683580

ELK4
ETS domain-containing protein Elk-4

2

1

High-throughput

0.521

High

389046

FINC
Fibronectin

1

6

Small-scale

0.501

High

547970

PSPC
Surfactant protein C

1

5

High-throughput

0.489

High

683598

SG2A2
Mammaglobin-A

1

2

High-throughput

0.489

High

683608

CA054
Uncharacterized protein C1orf54

1

5

High-throughput

0.489

High

683592

TSN5
Tetraspanin-5

1

20

High-throughput

0.484

High

683607

TSN14
Tetraspanin-14

1

20

High-throughput

0.484

High

138451

BIN1
Myc box-dependent-interacting protein 1

1

3

Small-scale

0.481

High

165166

TSN4
Tetraspanin-4

1

20

Small-scale

0.479

High

217850

TGON2
Trans-Golgi network integral membrane protein 2

1

9

High-throughput

0.479

High

374410

RASH
GTPase HRas

1

13

High-throughput

0.479

High

540315

LAMP1
Lysosome-associated membrane glycoprotein 1

1

5

High-throughput

0.479

High

635232

EFNA1
Ephrin-A1

1

3

High-throughput

0.479

High

642512

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

2

Small-scale

0.479

High

683579

CALR
Calreticulin

1

10

Small-scale

0.479

High

683585

CTNB1
Catenin beta-1

1

5

Small-scale

0.479

High

683586

VHL
von Hippel-Lindau disease tumor suppressor

1

4

Small-scale

0.479

High

683589

EFNA3
Ephrin-A3

1

3

High-throughput

0.479

High

683590

EFNA4
Ephrin-A4

1

3

High-throughput

0.479

High

683591

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

683593

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

683594

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

683596

CO4A3
Collagen alpha-3(IV) chain

1

5

Small-scale

0.479

High

683600

SMAD4
Mothers against decapentaplegic homolog 4

1

1

High-throughput

0.479

High

683603

CAH9
Carbonic anhydrase 9

1

6

High-throughput

0.479

High

683604

CSPG4
Chondroitin sulfate proteoglycan 4

1

5

Small-scale

0.479

High

683605

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

683611

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.479

High

683614

T106B
Transmembrane protein 106B

1

5

High-throughput

0.479

High

683584

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.458

High

160998

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

4

High-throughput

0.445

High

349377

TSN15
Tetraspanin-15

1

20

High-throughput

0.445

High

349622

TSN12
Tetraspanin-12

1

20

Small-scale

0.445

High

683599

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.445

High

683587

MSS4
Guanine nucleotide exchange factor MSS4

1

3

Small-scale

0.439

High

403835

GCR
Glucocorticoid receptor

1

1

High-throughput

0.437

High

674078

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.437

High

683595

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

170664

CLGN
Calmegin

1

10

High-throughput

0.407

High

683602

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.249

Low

683613

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025