HitPredict

Interactor 1: A5D6Q2 (A5D6Q2)
Ncoa3 protein
Gene: Ncoa3

Interactor 2: ERR2 (Q61539)
Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)
Gene: Esrrb

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20362541
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DUF4927~Hormone_recep, Hormone_recep~SRC-1
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1353 Mm			1 433
+	Mm
		985518 Q05BA5_MOUSE (1-1353): 1.49e-167: 540: 100.00		ERR2_MOUSE (1-433): 3.74e-165: 473: 100.00
+	Hs
		320237 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		ERR2_HUMAN (1-433): 4.41e-165: 473: 93.07
+	Mm
		60499 A5D6Q2_MOUSE (1-1353): 4.78e-168: 540: 100.00		HNF4G_MOUSE (93-429): 6.44e-108: 326: 28.78
+	Mm
		985528 Q05BA5_MOUSE (1-1353): 1.49e-167: 540: 100.00		HNF4G_MOUSE (93-429): 6.44e-108: 326: 28.78
+	Hs
		587212 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		RXRA_HUMAN (8-431): 1.52e-128: 381: 28.44
+	Hs
		320210 HIF1A_HUMAN (2-704): 1.09e-102: 348: 14.29		ERR2_HUMAN (1-433): 4.41e-165: 473: 93.07
+	Hs
		490120 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		COT1_HUMAN (26-429): 2.1e-119: 356: 29.31
+	Hs
		500381 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		RARB_HUMAN (41-430): 2.54e-115: 347: 28.32
+	Hs
		510047 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		ERR1_HUMAN (15-431): 7.01e-115: 344: 55.79
+	Hs
		370839 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		ESR1_HUMAN (10-432): 1.33e-111: 342: 33.05
+	Hs
		488043 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		RARA_HUMAN (38-430): 2.72e-111: 336: 27.64
+	Hs
		782708 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		HNF4A_HUMAN (78-429): 2.37e-109: 332: 28.61
+	Hs
		1025276 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		NR1H3_HUMAN (12-432): 1.7e-106: 324: 23.82
+	Hs
		530818 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		RARG_HUMAN (34-430): 2.15e-105: 321: 28.01
+	Hs
		874407 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		NR1H2_HUMAN (21-432): 2.72e-104: 319: 20.40
+	Hs
		611537 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		NR4A1_HUMAN (20-429): 3.05e-101: 315: 29.43
+	Hs
		500511 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		THB_HUMAN (23-430): 1.16e-101: 312: 25.23
+	Hs
		1270064 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		ESR2_HUMAN (102-433): 1.13e-69: 231: 38.61
+	Hs
		377843 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		GCR_HUMAN (99-352): 1.26e-45: 170: 37.98
+	Hs
		414535 NCOA3_HUMAN (1-1353): 1.22e-136: 456: 80.40		PRGR_HUMAN (92-369): 3.24e-45: 169: 31.08