Protein: CO4A1
Collagen alpha-1(IV) chain [Cleaved into: Arresten]

Gene: CO4A1, COL4A1
Organism: Homo sapiens
Interactions: 36
UniProt ID: P02462

Gene Ontology (top 5):
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0005587 - collagen type IV trimer
GO:0005201 - extracellular matrix structural constituent
GO:0005576 - extracellular region
GO:0005604 - basement membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

384320

C1QT1
Complement C1q tumor necrosis factor-related protein 1

2

20

High-throughput

0.776

High

384298

CO4A2

1

16

Small-scale

0.710

High

384307

CO8A1
Collagen alpha-1(VIII) chain

1

18

High-throughput

0.691

High

384297

MMP2
72 kDa type IV collagenase

3

20

High-throughput

0.662

High

384308

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

16

Small-scale

0.647

High

384311

CO7A1
Collagen alpha-1(VII) chain

1

17

Small-scale

0.647

High

384300

MMP9
Matrix metalloproteinase-9

2

20

High-throughput

0.628

High

384312

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

20

High-throughput

0.628

High

384317

GT252
Procollagen galactosyltransferase 2

2

20

High-throughput

0.628

High

384322

TINAG
Tubulointerstitial nephritis antigen

2

1

High-throughput

0.628

High

251837

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

2

20

High-throughput

0.601

High

384316

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

2

16

High-throughput

0.601

High

384309

VHL
von Hippel-Lindau disease tumor suppressor

3

4

Small-scale

0.585

High

384294

CO4A1

1

16

Small-scale

0.575

High

376366

PDGFB
Platelet-derived growth factor subunit B

1

11

Small-scale

0.536

High

215695

COCH
Cochlin

1

14

Small-scale

0.501

High

384295

PDGFA
Platelet-derived growth factor subunit A

1

11

Small-scale

0.501

High

384296

TSP1
Thrombospondin-1

1

8

Small-scale

0.501

High

384299

NID1
Nidogen-1

1

4

Small-scale

0.501

High

384302

PGS1
Biglycan

1

3

Small-scale

0.501

High

384303

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

4

Small-scale

0.501

High

384304

ACES
Acetylcholinesterase

1

1

Small-scale

0.501

High

384314

NID2
Nidogen-2

1

4

Small-scale

0.501

High

217689

TGON2
Trans-Golgi network integral membrane protein 2

1

8

High-throughput

0.479

High

384313

CUL3
Cullin-3

1

14

High-throughput

0.479

High

384301

MAG
Myelin-associated glycoprotein

1

5

Small-scale

0.457

High

384315

KLH22
Kelch-like protein 22

1

20

High-throughput

0.445

High

384319

KLK6
Kallikrein-6

1

5

Small-scale

0.445

High

384321

DISC1
Disrupted in schizophrenia 1 protein

1

3

Small-scale

0.439

High

60484

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

1

1

High-throughput

0.437

High

384305

CBL
E3 ubiquitin-protein ligase CBL

1

1

High-throughput

0.437

High

384306

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

1

High-throughput

0.437

High

333737

FKBP9
Peptidyl-prolyl cis-trans isomerase FKBP9

1

5

High-throughput

0.407

High

384318

KIFA3
Kinesin-associated protein 3

1

0

High-throughput

0.279

Low

384310

DCAF7
DDB1- and CUL4-associated factor 7

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025