HitPredict

Interactor 1: HXB9 (P17482)
Homeobox protein Hox-B9 (Homeobox protein Hox-2.5) (Homeobox protein Hox-2E)
Gene: HOXB9

Interactor 2: PCSK5 (Q92824)
Proprotein convertase subtilisin/kexin type 5 (EC 3.4.21.-) (Proprotein convertase 5) (PC5) (Proprotein convertase 6) (PC6) (hPC6) (Subtilisin/kexin-like protease PC5)
Gene: PCSK5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009952 - anterior/posterior pattern specification
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 1860
+	Hs
		885356 HXA1_HUMAN (10-247): 8.36e-31: 118: 24.17		PCSK5_HUMAN (1-1860): 0: 850: 100.00
+	Hs
		1232498 Q6FHY5_HUMAN (18-248): 6.87e-28: 109: 21.05		PCSK5_HUMAN (1-1860): 0: 850: 100.00
+	Hs
		270522 HXA1_HUMAN (10-247): 8.36e-31: 118: 24.17		MEGF6_HUMAN (537-1107): 1.91e-24: 114: 14.08
+	Hs
		885450 HXA1_HUMAN (10-247): 8.36e-31: 118: 24.17		NOTC3_HUMAN (1303-1753): 1.18e-20: 102: 11.33
+	Hs
		857376 HXA1_HUMAN (10-247): 8.36e-31: 118: 24.17		NOTC1_HUMAN (542-992): 1.04e-10: 69.3: 12.50