HitPredict

Interactor 1: XRN1 (P22147)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (DNA strand transfer protein beta) (STP-beta) (KAR(-)-enhancing mutation protein) (Strand exchange protein 1) (p175)
Gene: XRN1

Interactor 2: XRN1 (P22147)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (DNA strand transfer protein beta) (STP-beta) (KAR(-)-enhancing mutation protein) (Strand exchange protein 1) (p175)
Gene: XRN1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 37746059, 14759368
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_12~XRN1_D1, SH3_12~XRN1_D2_D3, SH3_12~XRN_N, XRN1_D1~XRN1_D2_D3, XRN1_D1~XRN_M, XRN1_D1~XRN_N, XRN1_D2_D3~XRN_M, XRN_M~XRN_M, XRN_M~XRN_N, XRN_N~XRN_N
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000741 - karyogamy
GO:0000932 - P-body
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003682 - chromatin binding
and 23 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1528
Sc

1 1528
+ Sc
+ Hs
+ Sc

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Last updated: 15 Jul 2024