Interactor 1: RAD53 (P22216)
Serine/threonine-protein kinase RAD53 (EC 2.7.12.1) (CHEK2 homolog) (Serine-protein kinase 1)
Gene: RAD53
Interactor 2: DUN1 (P39009)
DNA damage response protein kinase DUN1 (EC 2.7.11.1)
Gene: DUN1
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.969 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11805837, 9734355, 17299042, 12556502, 12917350, 18570878, 28858528, 19457865 |
| Identification Methods | anti tag coimmunoprecipitation, coimmunoprecipitation, affinity chromatography technology, unspecified method, pull down, enzymatic study |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | FHA~FHA, FHA~Pkinase, Pkinase~Pkinase |
| Common GO terms | GO:0000077 - DNA damage checkpoint signaling GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0004683 - calmodulin-dependent protein kinase activity GO:0005516 - calmodulin binding and 5 others more... |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
