Interactor 1: IL10 (P22301)
Interleukin-10 (IL-10) (Cytokine synthesis inhibitory factor) (CSIF)
Gene: IL10
Interactor 2: I10R1 (Q13651)
Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha) (IL-10R subunit alpha) (IL-10RA) (CDw210a) (Interleukin-10 receptor subunit 1) (IL-10R subunit 1) (IL-10R1) (CD antigen CD210)
Gene: IL10RA
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.980 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 8248239, 11485736, 7759550, 11717514, 10231374, 8120391, 15837194, 20462497, 9568901, 10788470, 12513909 |
| Identification Methods | biochemical, x-ray crystallography, pull down, affinity chromatography technology, surface plasmon resonance, isothermal titration calorimetry, filter binding, enzyme linked immunosorbent assay, molecular sieving |
| Interaction Type | association, direct interaction, physical association, enzymatic reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL10~Tissue_fac |
| Common GO terms | GO:0010507 - negative regulation of autophagy GO:0046427 - positive regulation of receptor signaling pathway via JAK-STAT GO:0050728 - negative regulation of inflammatory response GO:0050807 - regulation of synapse organization |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
