Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: RTN4R (Q9BZR6)
Reticulon-4 receptor (Nogo receptor) (NgR) (Nogo-66 receptor)
Gene: RTN4R

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~LRR_8, Ig_3~LRR_8, LRR_8~PK_Tyr_Ser-Thr
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0008201 - heparin binding
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 802
Hs

1 473
+ Mm
+ Dr
+ Dr
+ Hs
+ Mm
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Dr
+ Dr
+ Dr
+ Dr

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Last updated: 15 Jul 2024