HitPredict

Interactor 1: FGFR4 (P22455)
Fibroblast growth factor receptor 4 (FGFR-4) (EC 2.7.10.1) (CD antigen CD334)
Gene: FGFR4

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~I-set, PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 802 Hs			1 1129
+	Hs
		508262 FGFR1_HUMAN (3-794): 0: 706: 54.76		ASAP1_HUMAN (17-1129): 0: 831: 100.00
+	Hs
		195775 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		ASAP2_HUMAN (21-967): 0: 647: 55.31
+	Hs
		608050 FGFR4_HUMAN (13-802): 0: 750: 100.00		DP13B_HUMAN (45-453): 1.01e-98: 329: 16.03
+	Hs
		608182 FGFR4_HUMAN (13-802): 0: 750: 100.00		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		508261 FGFR1_HUMAN (3-794): 0: 706: 54.76		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		609490 FGFR3_HUMAN (5-799): 0: 712: 61.07		ARAP1_HUMAN (368-620): 3.83e-58: 222: 24.90
+	Hs
		1072626 EPHA7_HUMAN (4-781): 0: 584: 19.90		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		872503 EPHA5_HUMAN (4-771): 0: 580: 18.81		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		665358 EPHA2_HUMAN (4-789): 0: 573: 19.58		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		608061 FGFR4_HUMAN (13-802): 0: 750: 100.00		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		601555 FGFR2_HUMAN (4-797): 0: 737: 56.44		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		385190 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		DP13B_HUMAN (45-453): 1.01e-98: 329: 16.03
+	Hs
		1072629 EPHA7_HUMAN (4-781): 0: 584: 19.90		AGAP1_HUMAN (361-662): 1.75e-62: 231: 28.30
+	Hs
		1083906 NTRK2_HUMAN (114-757): 9.58e-166: 502: 25.84		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		1081642 NTRK3_HUMAN (159-751): 2.33e-165: 501: 25.24		DP13A_HUMAN (45-460): 7.54e-92: 312: 16.24
+	Hs
		91534 EPHA7_HUMAN (4-781): 0: 584: 19.90		E7EUN2_HUMAN (361-662): 1.85e-60: 227: 28.30
+	Hs
		508123 FGFR1_HUMAN (3-794): 0: 706: 54.76		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21
+	Hs
		385363 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		AGAP3_HUMAN (361-662): 1.44e-59: 223: 27.97
+	Hs
		385239 NTRK1_HUMAN (135-751): 4.91e-162: 491: 26.53		ARAP3_HUMAN (368-605): 4.78e-56: 215: 27.46
+	Hs
		872465 EPHA5_HUMAN (4-771): 0: 580: 18.81		SMAP2_HUMAN (436-549): 5.1e-16: 84: 36.21