Interactor 1: EGLN (P17813)
Endoglin (CD antigen CD105)
Gene: ENG

Interactor 2: BMP7 (P18075)
Bone morphogenetic protein 7 (BMP-7) (Osteogenic protein 1) (OP-1) (Eptotermin alfa)
Gene: BMP7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 9872992
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005615 - extracellular space
GO:0030509 - BMP signaling pathway
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0060391 - positive regulation of SMAD protein signal transduction
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 658
Hs

1 431
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 11Aug2025