HitPredict

Interactor 1: DDX5 (P17844)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5) (RNA helicase p68)
Gene: DDX5

Interactor 2: DHX9 (Q08211)
ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A)
Gene: DHX9

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.806

The method score is based on:

Property Details
Experiments 22365833, 35271311
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~HA2_N, DEAD~Helicase_C, Helicase_C~dsrm, HA2_C~Helicase_C, HA2_N~Helicase_C, Helicase_C~Helicase_C, Helicase_C~OB_NTP_bind
Common GO terms GO:0000380 - alternative mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0003729 - mRNA binding
GO:0005524 - ATP binding
and 11 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 614
Hs

1 1270
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Service provided by Combinatics, Japan

Last updated: 11Aug2025