HitPredict

Interactor 1: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Interactor 2: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 25416956, 28292943, 32296183, 37256937, 25253489, 21675959, 8419915, unassigned1304
Identification Methods two hybrid, pull down, affinity chromatography technology, cross-linking study, protein complementation assay, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB_C~Prot_ATP_ID_OB_C
Common GO terms GO:0000502 - proteasome complex
GO:0000932 - P-body
GO:0001824 - blastocyst development
GO:0005524 - ATP binding
GO:0005576 - extracellular region
and 14 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 439
Hs

1 439
+ At
+ Hs
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+ At
+ At
+ At
+ At
+ At
+ Hs
+ Af
+ Hs
+ Hs
+ At
+ Hs
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+ Rn
+ At
+ Hs

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Last updated: 11Aug2025