Interactor 1: PRS7 (P35998)
26S proteasome regulatory subunit 7 (26S proteasome AAA-ATPase subunit RPT1) (Proteasome 26S subunit ATPase 2)
Gene: PSMC2

Interactor 2: Q53HB3 (Q53HB3)
26S proteasome regulatory subunit 4 (26S proteasome AAA-ATPase subunit RPT2) (Proteasome 26S subunit ATPase 1)
Gene: Q53HB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25036637
Identification Methods luminescence based mammalian interactome mapping
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, AAA_lid_3~AAA_lid_3, AAA~PRS7_OB, PRS7_OB~Prot_ATP_ID_OB_C
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0016887 - ATP hydrolysis activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 433
Hs

1 440
+ Dm
+ Hs
+ Dm
+ Sc
+ Dm
+ At
+ Hs
+ Dm
+ Hs
+ Dm
+ Sc
+ Hs
+ Hs
+ Rn
+ Dm
+ Dm
+ Hs
+ Sc
+ Hs
+ Dm

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Last updated: 11Aug2025