Interactor 1: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL
Interactor 2: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.58 | 0.60 | 0.594 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25814554, unassigned1126 |
Identification Methods | two hybrid, two hybrid array, validated two hybrid |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0019221 - cytokine-mediated signaling pathway |
Homologous interactions | 3 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024