HitPredict

Interactor 1: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 439 Hs			1 156
+	Hs
		778654 PRS7_HUMAN (21-433): 3.78e-124: 369: 37.35		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		968871 PRS8_HUMAN (65-437): 1.52e-124: 369: 44.39		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Dm
		583696 Q9V3V6_DROME (26-439): 3.71e-127: 376: 85.75		RS27A_DROME (1-156): 1.19e-72: 216: 91.03
+	At
		1168355 PRS4A_ARATH (34-433): 6.62e-155: 447: 44.06		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Rn
		1224400 PRS6A_RAT (1-439): 9.81e-139: 406: 99.32		UBC_RAT (1-119): 1.58e-36: 134: 68.29
+	Mm
		312776 PRS6A_MOUSE (1-439): 2.2e-138: 405: 99.32		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	Hs
		968680 PRS4_HUMAN (32-433): 9.24e-134: 393: 43.60		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Mm
		509013 PRS4_MOUSE (32-433): 9.24e-134: 393: 43.60		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	Rn
		968862 PRS4_RAT (32-433): 9.24e-134: 393: 43.60		UBC_RAT (1-119): 1.58e-36: 134: 68.29
+	Hs
		968872 PRS8_HUMAN (65-437): 1.52e-124: 369: 44.39		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	At
		1168248 PS6AA_ARATH (30-439): 2.01e-128: 379: 78.35		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Mm
		509014 PRS8_MOUSE (65-437): 1.52e-124: 369: 44.39		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	At
		1168250 PRS6B_ARATH (38-438): 5.45e-126: 372: 38.40		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		146210 PS6AB_ARATH (30-439): 6.39e-125: 370: 77.13		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Mm
		508991 PRS6B_MOUSE (8-438): 2.65e-120: 358: 37.59		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	Rn
		1224401 PRS6B_RAT (8-438): 2.65e-120: 358: 37.59		UBC_RAT (1-119): 1.58e-36: 134: 68.29
+	Hs
		507108 PRS6B_HUMAN (8-438): 2.68e-121: 361: 37.59		UBB_HUMAN (1-76): 6.68e-36: 125: 100.00
+	At
		1167868 PRS8B_ARATH (28-438): 3.67e-120: 358: 41.16		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		1167904 PRS8A_ARATH (28-438): 2.95e-120: 358: 40.92		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		1168320 PRS7A_ARATH (26-433): 6.87e-120: 357: 38.20		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81