Protein: Q9V3V6
26S proteasome regulatory complex subunit p50 (GH12068p) (Regulatory particle triple-A ATPase 5 (EC 5.6.1.5))

Gene: Q9V3V6, Rpt5
Organism: Drosophila melanogaster
Interactions: 178
UniProt ID: Q9V3V6

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005838 - proteasome regulatory particle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1464497

Q9W414
Regulatory particle triple-A ATPase 4

3

20

High-throughput

0.821

High

1464440

PSMD9
26S proteasome non-ATPase regulatory subunit 9

3

13

Small-scale

0.817

High

90544

C1C3F8
LP16188p

2

19

High-throughput

0.770

High

47782

A0AQH0
Proteasome subunit beta

2

20

High-throughput

0.737

High

198066

PRS8
26S proteasome regulatory subunit 8

2

17

High-throughput

0.737

High

556722

PSA1
Proteasome subunit alpha type-1

2

20

High-throughput

0.737

High

611510

PSA4
Proteasome subunit alpha type-4

2

20

High-throughput

0.737

High

652767

PSA71
Proteasome subunit alpha type-7-1

2

20

High-throughput

0.737

High

684558

PSMD7
26S proteasome non-ATPase regulatory subunit 7

2

20

High-throughput

0.737

High

821881

PSA2
Proteasome subunit alpha type-2

2

20

High-throughput

0.737

High

822069

PSB1
Proteasome subunit beta type-1

2

20

High-throughput

0.737

High

874997

PRS4
26S proteasome regulatory subunit 4

2

20

High-throughput

0.737

High

1264683

Q7K148
Proteasome subunit beta

2

20

High-throughput

0.737

High

1267700

Q7KMQ0
26S proteasome regulatory subunit 7

2

20

High-throughput

0.737

High

1376921

PSA5
Proteasome subunit alpha type-5

2

20

High-throughput

0.737

High

1463471

PSMD6
26S proteasome non-ATPase regulatory subunit 6

2

20

High-throughput

0.737

High

1463622

PSDE
26S proteasome non-ATPase regulatory subunit 14

2

20

High-throughput

0.737

High

1464418

Q9V3Z4
GH11341p

2

20

High-throughput

0.737

High

1464419

Q9V405
26S proteasome regulatory subunit 6B

2

19

High-throughput

0.737

High

1464426

PSA3
Proteasome subunit alpha type-3

2

20

High-throughput

0.737

High

1464450

Q9VJJ0
Proteasome subunit beta

2

20

High-throughput

0.737

High

1464459

PSB4
Proteasome subunit beta type-4

2

20

High-throughput

0.737

High

1464471

Q9VUJ1
Proteasome subunit beta

2

20

High-throughput

0.737

High

1464475

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

2

20

High-throughput

0.737

High

1464499

PSB3
Proteasome subunit beta type-3

2

20

High-throughput

0.737

High

1464477

Q9VWD9
Ubiquilin-like protein

1

20

Small-scale

0.647

High

583696

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

20

Small-scale

0.618

High

1464501

PSA6
Proteasome subunit alpha type-6

1

20

High-throughput

0.618

High

1346048

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

17

High-throughput

0.575

High

1464455

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

18

High-throughput

0.575

High

669711

PSMD3
Probable 26S proteasome non-ATPase regulatory subunit 3

2

19

High-throughput

0.571

High

875255

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.571

High

1059160

ROP
Protein ROP

2

8

High-throughput

0.571

High

1265198

ADRM1
Proteasomal ubiquitin receptor ADRM1 homolog

2

11

High-throughput

0.571

High

1267337

PSD11
26S proteasome non-ATPase regulatory subunit 11

2

20

High-throughput

0.571

High

1267662

Q7KMP8
26S proteasome non-ATPase regulatory subunit 13

2

18

High-throughput

0.571

High

1464084

PSMD1
26S proteasome non-ATPase regulatory subunit 1

2

20

High-throughput

0.571

High

1464427

Q9V9Q4
LD43819p

2

6

High-throughput

0.571

High

1464436

Q9VEC2
Proteasome assembly chaperone 2

2

5

High-throughput

0.571

High

1464484

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

16

High-throughput

0.571

High

1464495

Q9W392
T-complex protein 1 subunit beta

2

20

High-throughput

0.571

High

1464443

Q9VGU4
FI02822p

1

9

High-throughput

0.536

High

715133

CLH
Clathrin heavy chain

2

6

High-throughput

0.521

High

1268166

Q7KN94
Electron transfer flavoprotein subunit alpha

2

5

High-throughput

0.521

High

1464474

Q9VV75
AT02348p

2

7

High-throughput

0.521

High

460098

ALF
Fructose-bisphosphate aldolase

1

3

High-throughput

0.484

High

385001

HSP27
Heat shock protein 27

1

4

Small-scale

0.479

High

541221

KRAF1
Raf homolog serine/threonine-protein kinase Raf

1

5

High-throughput

0.479

High

654314

DDX6
ATP-dependent RNA helicase me31b

1

12

High-throughput

0.479

High

1172639

SIMA
Protein similar

1

12

High-throughput

0.479

High

1303704

AKT1
RAC serine/threonine-protein kinase

1

10

High-throughput

0.479

High

1306385

Q8IRH0
Puromycin-sensitive aminopeptidase

1

9

High-throughput

0.479

High

1464439

Q9VEV3
Tetratricopeptide repeat protein 1

1

18

High-throughput

0.479

High

1464448

Q9VIJ5
GEO05038p1

1

4

High-throughput

0.479

High

1464493

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

20

High-throughput

0.479

High

1464467

Q9VSE9
Estrogen-related receptor

1

20

High-throughput

0.451

High

55797

A1Z9K0
Uncharacterized protein, isoform B

1

5

High-throughput

0.445

High

58095

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

16

High-throughput

0.445

High

119001

M9NFI9
Neurabin-1

1

3

High-throughput

0.445

High

197082

O18332
FI01544p

1

5

High-throughput

0.445

High

565010

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

11

High-throughput

0.445

High

652071

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

12

High-throughput

0.445

High

704372

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

15

High-throughput

0.445

High

782751

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

10

High-throughput

0.445

High

823781

SQH
Myosin regulatory light chain sqh

1

8

High-throughput

0.445

High

829657

ARF4
ADP ribosylation factor 4

1

10

High-throughput

0.445

High

834860

IF2B
Eukaryotic translation initiation factor 2 subunit 2

1

4

High-throughput

0.445

High

852953

ACTZ
Actin-related protein 1

1

12

High-throughput

0.445

High

909867

PFKA
ATP-dependent 6-phosphofructokinase

1

9

High-throughput

0.445

High

1057341

ARL2
ADP-ribosylation factor-like protein 2

1

17

High-throughput

0.445

High

1069748

Q0E931
GTP-binding protein 1

1

10

High-throughput

0.445

High

1070097

Q0E9E2
Pyruvate carboxylase

1

12

High-throughput

0.445

High

1173929

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

9

High-throughput

0.445

High

1176001

MCM4
DNA replication licensing factor MCM4

1

3

High-throughput

0.445

High

1176295

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

14

High-throughput

0.445

High

1234104

SARM1
NAD(+) hydrolase sarm1

1

11

High-throughput

0.445

High

1265807

Q7K3J0
T-complex protein 1 subunit theta

1

20

High-throughput

0.445

High

1267254

Q7KKI0
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.445

High

1321437

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

10

High-throughput

0.445

High

1344105

Q8SY39
ATP-dependent RNA helicase DDX54

1

15

High-throughput

0.445

High

1344227

Q8SY53
GH11935p

1

3

High-throughput

0.445

High

1344416

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

5

High-throughput

0.445

High

1346257

Q8T8W3
AT21416p

1

6

High-throughput

0.445

High

1376847

LDH
L-lactate dehydrogenase

1

10

High-throughput

0.445

High

1378462

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

11

High-throughput

0.445

High

1440564

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

3

High-throughput

0.445

High

1457438

XPO1
Exportin-1

1

11

High-throughput

0.445

High

1463809

JIL1
Chromosomal serine/threonine-protein kinase JIL-1

1

13

High-throughput

0.445

High

1464421

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

13

High-throughput

0.445

High

1464422

Q9V436
26S proteasome non-ATPase regulatory subunit 8

1

11

High-throughput

0.445

High

1464424

Q9V455
Importin subunit alpha

1

7

High-throughput

0.445

High

1464425

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

1

11

High-throughput

0.445

High

1464430

Q9VAH7
N-terminal kinase-like protein

1

4

High-throughput

0.445

High

1464432

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

11

High-throughput

0.445

High

1464434

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

11

High-throughput

0.445

High

1464438

Q9VEP0
Regulatory protein zeste

1

2

High-throughput

0.445

High

1464441

ELP6
Elongator complex protein 6

1

1

High-throughput

0.445

High

1464442

IPO9
Importin-9

1

10

High-throughput

0.445

High

1464444

Q9VHL2
T-complex protein 1 subunit eta

1

19

High-throughput

0.445

High

1464445

ARL8
ADP-ribosylation factor-like protein 8

1

12

High-throughput

0.445

High

1464446

Q9VI53
LD44267p

1

9

High-throughput

0.445

High

1464447

DDX47
ATP-dependent RNA helicase DDX47

1

13

High-throughput

0.445

High

1464451

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

5

High-throughput

0.445

High

1464452

Q9VK69
T-complex protein 1 subunit delta

1

18

High-throughput

0.445

High

1464453

NFS1
Cysteine desulfurase, mitochondrial

1

5

High-throughput

0.445

High

1464458

Q9VN44
FI07923p

1

11

High-throughput

0.445

High

1464462

Q9VQI5
Interferon-related developmental regulator 1

1

3

High-throughput

0.445

High

1464463

Q9VQL1
serine--tRNA ligase

1

16

High-throughput

0.445

High

1464466

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

1

5

High-throughput

0.445

High

1464470

FRL
Formin-like protein

1

6

High-throughput

0.445

High

1464472

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

4

High-throughput

0.445

High

1464480

Q9VWI2
N(Alpha)-acetyltransferase 15/16, isoform A

1

12

High-throughput

0.445

High

1464483

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.445

High

1464485

Q9VXR5
ATP-binding cassette sub-family F member 2

1

13

High-throughput

0.445

High

1464487

RENT1
Regulator of nonsense transcripts 1 homolog

1

5

High-throughput

0.445

High

1464488

Q9VZ88
AT07585p

1

6

High-throughput

0.445

High

1464491

Q9W0E4
Aminopeptidase

1

9

High-throughput

0.445

High

1464503

SYQ
Probable glutamine--tRNA ligase

1

10

High-throughput

0.445

High

1355799

Q8WS79
Estrogen-related receptor splice variant

1

20

High-throughput

0.439

High

52684

A1Z729
NADP-retinol dehydrogenase

1

12

High-throughput

0.437

High

119599

M9PAY7
Pi3K21B, isoform C

1

6

High-throughput

0.437

High

1464460

Q9VNI4
Proteasome assembly chaperone 1

1

4

High-throughput

0.437

High

1464461

Q9VPP7
AT13539p

1

2

High-throughput

0.437

High

1464489

Q9VZL3
very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

53144

A1Z7K8
AaRS-interacting multifunctional protein 1

1

4

High-throughput

0.407

High

53689

A1Z843
Nodal modulator 3

1

1

High-throughput

0.407

High

55453

A1Z9E3
Elongation factor Tu

1

4

High-throughput

0.407

High

144887

ATPG
ATP synthase subunit gamma, mitochondrial

1

6

High-throughput

0.407

High

263390

PENG
Protein penguin

1

2

High-throughput

0.407

High

304233

ERD2
ER lumen protein-retaining receptor

1

3

High-throughput

0.407

High

355958

O96692
small monomeric GTPase

1

13

High-throughput

0.407

High

360559

COX2
Cytochrome c oxidase subunit 2

1

4

High-throughput

0.407

High

852203

COPB
Coatomer subunit beta

1

9

High-throughput

0.407

High

1069176

Q0E8E8
Phosphate carrier protein, mitochondrial

1

8

High-throughput

0.407

High

1071028

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

4

High-throughput

0.407

High

1173561

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.407

High

1236873

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

8

High-throughput

0.407

High

1237015

Q6NP72
GEO09659p1

1

3

High-throughput

0.407

High

1263214

Q7JXU4
Nucleolar GTP-binding protein 2

1

5

High-throughput

0.407

High

1264520

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

4

High-throughput

0.407

High

1266924

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

4

High-throughput

0.407

High

1267529

NITO
RNA-binding protein spenito

1

5

Small-scale

0.407

High

1268342

DYM
Dymeclin

1

2

High-throughput

0.407

High

1268705

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

6

High-throughput

0.407

High

1304765

Q8IPU8
BNIP3, isoform B

1

4

High-throughput

0.407

High

1343132

Q8STG9
DSec61alpha

1

5

High-throughput

0.407

High

1378623

Q95WY3
Nucleolar protein 56

1

6

High-throughput

0.407

High

1378821

Q960C7
NADP-retinol dehydrogenase

1

12

High-throughput

0.407

High

1464420

API5
Apoptosis inhibitor 5 homolog

1

2

High-throughput

0.407

High

1464423

KRH2
Krueppel homolog 2

1

2

High-throughput

0.407

High

1464428

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.407

High

1464431

Q9VAL7
Calnexin 99A, isoform A

1

6

High-throughput

0.407

High

1464433

Q9VCF8
LD23561p

1

1

High-throughput

0.407

High

1464435

Q9VDK7
Signal recognition particle subunit SRP72

1

2

High-throughput

0.407

High

1464437

Q9VEH0
Aluminum tubes, isoform A

1

20

High-throughput

0.407

High

1464449

Q9VJD1
Glucosidase 2 subunit beta

1

6

High-throughput

0.407

High

1464454

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

17

High-throughput

0.407

High

1464456

Q9VM57
Septin interacting protein 2, isoform A

1

1

High-throughput

0.407

High

1464457

Q9VM97
Thrombospondin, isoform A

1

2

High-throughput

0.407

High

1464464

Q9VQL7
Fatty acid synthase

1

7

High-throughput

0.407

High

1464465

Q9VS47
Lysosomal dipeptide transporter MFSD1

1

1

High-throughput

0.407

High

1464468

SRP68
Signal recognition particle subunit SRP68

1

5

High-throughput

0.407

High

1464469

ODR4
Protein odr-4 homolog

1

2

High-throughput

0.407

High

1464473

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

5

High-throughput

0.407

High

1464476

Q9VW70
FI21813p1

1

2

High-throughput

0.407

High

1464478

RS10B
Small ribosomal subunit protein eS10B

1

11

High-throughput

0.407

High

1464479

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

9

High-throughput

0.407

High

1464481

Q9VWL0
Mec2

1

8

High-throughput

0.407

High

1464482

Q9VXG0
Cell division cycle 50, isoform A

1

4

High-throughput

0.407

High

1464486

Q9VXV6
Secretory carrier-associated membrane protein

1

1

High-throughput

0.407

High

1464490

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

2

High-throughput

0.407

High

1464492

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

4

High-throughput

0.407

High

1464494

Q9W1H8
acetyl-CoA C-acyltransferase

1

10

High-throughput

0.407

High

1464496

Q9W3N1
RH59310p

1

4

High-throughput

0.407

High

1464498

Q9W4N8
LD30122p

1

9

High-throughput

0.407

High

1464500

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

4

High-throughput

0.407

High

1464502

FL2D
Pre-mRNA-splicing regulator female-lethal(2)D

1

6

Small-scale

0.407

High

1464429

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025