HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: FYN (P39688)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)
Gene: FYN

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.722

The method score is based on:

Property Details
Experiments 19734451, 8551236, 9890970, 8635998, 9210408, 27474268
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007166 - cell surface receptor signaling pathway
GO:0016567 - protein ubiquitination
GO:0036120 - cellular response to platelet-derived growth factor stimulus
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 913
Mm

1 537
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024