Protein: RBX2
RING-box protein 2 (Rbx2) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)

Gene: RBX2, RNF7
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q9UBF6

Gene Ontology (top 5):
GO:0005507 - copper ion binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1274072

CUL5
Cullin-5

26

20

Small-scale

0.993

High

849472

UB2D1
Ubiquitin-conjugating enzyme E2 D1

11

20

Small-scale

0.977

High

1281717

UBE2F
NEDD8-conjugating enzyme UBE2F

9

20

Small-scale

0.968

High

1041242

CUL1
Cullin-1

7

20

Small-scale

0.953

High

135956

UBE2C
Ubiquitin-conjugating enzyme E2 C

4

20

Small-scale

0.899

High

919890

UB2D2
Ubiquitin-conjugating enzyme E2 D2

4

20

Small-scale

0.896

High

1072474

ELOB
Elongin-B

4

1

Small-scale

0.893

High

895936

UB2D3
Ubiquitin-conjugating enzyme E2 D3

4

20

Small-scale

0.885

High

1086932

UBE2S
Ubiquitin-conjugating enzyme E2 S

3

20

Small-scale

0.861

High

1043275

CUL4A
Cullin-4A

3

20

Small-scale

0.854

High

828041

UB2R1
Ubiquitin-conjugating enzyme E2 R1

3

20

Small-scale

0.845

High

1043627

CUL4B
Cullin-4B

2

20

Small-scale

0.799

High

1041486

CUL2
Cullin-2

2

20

Small-scale

0.767

High

1042735

CUL3
Cullin-3

2

20

Small-scale

0.755

High

1354003

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.698

High

1347546

ASB6
Ankyrin repeat and SOCS box protein 6

4

5

Small-scale

0.697

High

1219383

CUL9
Cullin-9

1

9

High-throughput

0.691

High

1301661

RB40C
Ras-related protein Rab-40C

3

11

Small-scale

0.676

High

1354002

FBW1A
F-box/WD repeat-containing protein 1A

3

14

Small-scale

0.664

High

1192666

UB2Q1
Ubiquitin-conjugating enzyme E2 Q1

1

0

High-throughput

0.663

High

1332213

ASB7
Ankyrin repeat and SOCS box protein 7

3

7

Small-scale

0.662

High

1017283

RB40B
Ras-related protein Rab-40B

3

11

Small-scale

0.656

High

1300103

ASB2
Ankyrin repeat and SOCS box protein 2

3

2

Small-scale

0.650

High

312674

ARI2
E3 ubiquitin-protein ligase ARIH2

1

9

Small-scale

0.647

High

896246

UBC12
NEDD8-conjugating enzyme Ubc12

1

20

Small-scale

0.647

High

932589

UB2L3
Ubiquitin-conjugating enzyme E2 L3

1

20

Small-scale

0.647

High

1273414

GLMN
Glomulin

1

1

Small-scale

0.647

High

1353996

RBX2
RING-box protein 2

1

13

Small-scale

0.647

High

808306

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

5

Small-scale

0.629

High

934533

CSK21
Casein kinase II subunit alpha

2

2

Small-scale

0.629

High

1305212

SPSB2
SPRY domain-containing SOCS box protein 2

2

7

Small-scale

0.628

High

931914

CSK2B
Casein kinase II subunit beta

3

0

Small-scale

0.627

High

1354006

ASB1
Ankyrin repeat and SOCS box protein 1

2

11

Small-scale

0.621

High

147449

SOCS3
Suppressor of cytokine signaling 3

2

10

Small-scale

0.619

High

146650

SOCS2
Suppressor of cytokine signaling 2

2

9

Small-scale

0.611

High

1071631

LRC41
Leucine-rich repeat-containing protein 41

2

1

Small-scale

0.611

High

1264023

ASB13
Ankyrin repeat and SOCS box protein 13

2

8

High-throughput

0.611

High

1283474

SPSB4
SPRY domain-containing SOCS box protein 4

2

8

Small-scale

0.611

High

1354007

WSB1
WD repeat and SOCS box-containing protein 1

2

6

Small-scale

0.611

High

1072323

ELOC
Elongin-C

2

2

Small-scale

0.602

High

1047468

PEBB
Core-binding factor subunit beta

2

1

Small-scale

0.595

High

1354008

NEMO
NF-kappa-B essential modulator

1

7

High-throughput

0.594

High

1315458

CAR14
Caspase recruitment domain-containing protein 14

1

1

Small-scale

0.552

High

851293

MAT1
CDK-activating kinase assembly factor MAT1

1

1

High-throughput

0.541

High

1190461

TRI46
Tripartite motif-containing protein 46

1

5

High-throughput

0.541

High

1290124

CHFR
E3 ubiquitin-protein ligase CHFR

1

2

High-throughput

0.541

High

1318356

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

4

High-throughput

0.541

High

146699

SOCS7
Suppressor of cytokine signaling 7

1

8

High-throughput

0.536

High

147569

SOCS6
Suppressor of cytokine signaling 6

1

10

High-throughput

0.536

High

154257

CHK1
Serine/threonine-protein kinase Chk1

1

2

High-throughput

0.536

High

238819

UGDH
UDP-glucose 6-dehydrogenase

1

1

High-throughput

0.536

High

256860

SOCS5
Suppressor of cytokine signaling 5

1

9

High-throughput

0.536

High

830494

KC1E
Casein kinase I isoform epsilon

1

5

High-throughput

0.536

High

987006

SUH
Recombining binding protein suppressor of hairless

1

1

High-throughput

0.536

High

1162014

SPSB3
SPRY domain-containing SOCS box protein 3

1

9

High-throughput

0.536

High

1202162

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

5

High-throughput

0.536

High

1260138

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

3

High-throughput

0.536

High

1261308

RN138
E3 ubiquitin-protein ligase RNF138

1

2

High-throughput

0.536

High

1263837

SOCS4
Suppressor of cytokine signaling 4

1

11

High-throughput

0.536

High

1265909

DDB2
DNA damage-binding protein 2

1

7

High-throughput

0.536

High

1284740

TTC28
Tetratricopeptide repeat protein 28

1

1

High-throughput

0.536

High

1285417

SPSB1
SPRY domain-containing SOCS box protein 1

1

8

Small-scale

0.536

High

1288472

TBC31
TBC1 domain family member 31

1

3

High-throughput

0.536

High

1297876

PCMD1
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1

1

1

High-throughput

0.536

High

1316335

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

1

3

High-throughput

0.536

High

1329149

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

1

High-throughput

0.536

High

1332866

ASB8
Ankyrin repeat and SOCS box protein 8

1

7

High-throughput

0.536

High

1334405

CSN7B
COP9 signalosome complex subunit 7b

1

2

High-throughput

0.536

High

1344886

TULP4
Tubby-related protein 4

1

2

High-throughput

0.536

High

1345543

CISH
Cytokine-inducible SH2-containing protein

1

9

High-throughput

0.536

High

1346363

PCMD2
Protein-L-isoaspartate O-methyltransferase domain-containing protein 2

1

1

High-throughput

0.536

High

1348662

WSB2
WD repeat and SOCS box-containing protein 2

1

7

High-throughput

0.536

High

1354005

ASB3
Ankyrin repeat and SOCS box protein 3

1

4

High-throughput

0.536

High

1023577

MKRN3
Probable E3 ubiquitin-protein ligase makorin-3

1

0

High-throughput

0.518

High

1264032

ASB12
Ankyrin repeat and SOCS box protein 12

1

6

Small-scale

0.515

High

316355

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

0

High-throughput

0.513

High

581069

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.513

High

819437

GSH0
Glutamate--cysteine ligase regulatory subunit

1

0

High-throughput

0.513

High

841024

MAP2
Methionine aminopeptidase 2

1

0

High-throughput

0.513

High

1078956

TBCE
Tubulin-specific chaperone E

1

0

High-throughput

0.513

High

1168150

KAT3
Kynurenine--oxoglutarate transaminase 3

1

0

High-throughput

0.513

High

1287817

NMD3
60S ribosomal export protein NMD3

1

0

High-throughput

0.513

High

1310349

PDD2L
Programmed cell death protein 2-like

1

0

High-throughput

0.513

High

1353997

STK39
STE20/SPS1-related proline-alanine-rich protein kinase

1

0

High-throughput

0.513

High

874349

GEM
GTP-binding protein GEM

1

9

High-throughput

0.508

High

1045371

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

1

Small-scale

0.501

High

1216959

ABC3F
DNA dC->dU-editing enzyme APOBEC-3F

1

1

High-throughput

0.501

High

1263829

ASB11
Ankyrin repeat and SOCS box protein 11

1

6

Small-scale

0.501

High

1299656

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

5

High-throughput

0.501

High

1301461

ERBIN
Erbin

1

1

Small-scale

0.501

High

1335662

ABC3G
DNA dC->dU-editing enzyme APOBEC-3G

1

1

High-throughput

0.501

High

1343940

ITM2C
Integral membrane protein 2C

1

1

High-throughput

0.494

High

1220308

DHX40
Probable ATP-dependent RNA helicase DHX40

1

2

High-throughput

0.489

High

517513

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.484

High

1270813

CBP
CREB-binding protein

1

2

Small-scale

0.481

High

1346466

UBP40
Ubiquitin carboxyl-terminal hydrolase 40

1

1

Small-scale

0.481

High

1252664

UBA3
NEDD8-activating enzyme E1 catalytic subunit

1

0

Small-scale

0.480

High

772190

VHL
von Hippel-Lindau disease tumor suppressor

1

3

Small-scale

0.479

High

788231

CASP3
Caspase-3

1

4

Small-scale

0.479

High

875388

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.479

High

989407

PRDX1
Peroxiredoxin-1

1

5

Small-scale

0.479

High

1031293

SKP2
S-phase kinase-associated protein 2

1

8

Small-scale

0.479

High

1045552

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

3

High-throughput

0.479

High

1161499

DCNL2
DCN1-like protein 2

1

9

Small-scale

0.479

High

1218601

DCNL3
DCN1-like protein 3

1

9

Small-scale

0.479

High

1263858

ASB10
Ankyrin repeat and SOCS box protein 10

1

5

High-throughput

0.479

High

1267356

DCNL4
DCN1-like protein 4

1

9

Small-scale

0.479

High

1312194

DCNL5
DCN1-like protein 5

1

9

Small-scale

0.479

High

1331524

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

1353998

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1353999

FBW1B
F-box/WD repeat-containing protein 11

1

14

Small-scale

0.479

High

1354000

FZR1
Fizzy-related protein homolog

1

5

Small-scale

0.479

High

1354004

ASB4
Ankyrin repeat and SOCS box protein 4

1

5

High-throughput

0.479

High

1166426

CLC4G
C-type lectin domain family 4 member G

1

5

High-throughput

0.417

High

500975

GHR
Growth hormone receptor

1

1

Small-scale

0.408

High

327596

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.279

Low

1125297

DALD3
DALR anticodon-binding domain-containing protein 3

1

0

High-throughput

0.279

Low

1266239

DHB8
(3R)-3-hydroxyacyl-CoA dehydrogenase

1

0

High-throughput

0.279

Low

1335437

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

1354001

EPDR1
Mammalian ependymin-related protein 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024