HitPredict

Interactor 1: XPA (P23025)
DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein)
Gene: XPA

Interactor 2: XPF (Q92889)
DNA repair endonuclease XPF (EC 3.1.-.-) (DNA excision repair protein ERCC-4) (DNA repair protein complementing XP-F cells) (Xeroderma pigmentosum group F-complementing protein)
Gene: ERCC4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.696

The method score is based on:

Property	Details
Experiments	26186194, 28514442, 9013642, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000110 - nucleotide-excision repair factor 1 complex GO:0003684 - damaged DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair and 3 others more... GO:0006289 - nucleotide-excision repair GO:0009650 - UV protection GO:1901255 - nucleotide-excision repair involved in interstrand cross-link repair
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	273
Hs

1	916

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024