Protein: DFD
Homeotic protein deformed

Gene: DFD
Organism: Drosophila melanogaster
Interactions: 32
UniProt ID: P07548

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

458216

EXD
Homeobox protein extradenticle

2

20

Small-scale

0.768

High

458213

BCD
Homeotic protein bicoid

1

20

High-throughput

0.656

High

458215

ABDA
Homeobox protein abdominal-A

1

20

High-throughput

0.621

High

458220

UBX
Homeotic protein ultrabithorax

1

20

High-throughput

0.621

High

458237

MED19
Mediator of RNA polymerase II transcription subunit 19

1

5

Small-scale

0.552

High

458214

CDK2
Cyclin-dependent kinase 2

1

10

High-throughput

0.508

High

458217

CDK5
Cyclin-dependent kinase 5 homolog

1

10

High-throughput

0.508

High

458219

POLO
Serine/threonine-protein kinase polo

1

7

High-throughput

0.508

High

458221

Q7K306
cyclin-dependent kinase

1

11

High-throughput

0.508

High

458224

CYCG
Cyclin G

1

5

High-throughput

0.508

High

458228

Q9VEH1
LD04521p

1

10

High-throughput

0.508

High

458234

Q9VRQ2
Mitotic spindle assembly checkpoint protein MAD2A

1

4

High-throughput

0.508

High

458236

ORB2
Translational regulator orb2

1

5

High-throughput

0.508

High

458240

RTEL1
Regulator of telomere elongation helicase 1 homolog

1

1

High-throughput

0.508

High

458218

RUX
Cell cycle negative regulator roughex

1

0

High-throughput

0.486

High

458239

Q9W102
Origin recognition complex subunit 4

1

0

High-throughput

0.486

High

235148

O46308
non-specific serine/threonine protein kinase

1

7

High-throughput

0.481

High

458235

Q9VSE6
ATP-dependent DNA helicase Q4

1

10

High-throughput

0.481

High

145774

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

5

High-throughput

0.464

High

458230

Q9VHN1
Cyclin-dependent kinases regulatory subunit

1

3

High-throughput

0.464

High

458223

Q8SZA4
non-specific serine/threonine protein kinase

1

4

High-throughput

0.457

High

458226

Q9NH11
DNA 3'-5' helicase

1

10

High-throughput

0.457

High

458227

Q9V475
Cullin 3, isoform C

1

6

High-throughput

0.457

High

84615

B7Z028
Acyl-coenzyme A oxidase

1

3

High-throughput

0.439

High

458222

Q8IP45
Cullin 3, isoform F

1

6

High-throughput

0.439

High

458229

Q9VGQ0
Serine/threonine-protein kinase par-1

1

2

High-throughput

0.439

High

458238

Q9VXR9
FI03680p

1

1

High-throughput

0.439

High

195898

O17049
Serine/threonine-protein kinase par-1

1

2

High-throughput

0.417

High

458225

Q961V9
GH03273p

1

1

High-throughput

0.417

High

458232

Q9VMD7
Acyl-coenzyme A oxidase

1

3

High-throughput

0.417

High

458231

MPPE1
Metallophosphoesterase 1 homolog

1

0

High-throughput

0.265

Low

458233

Q9VMJ2
RT07854p

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025