HitPredict

Interactor 1: ITA6 (P23229)
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
Gene: ITGA6

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0043065 - positive regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 196
+	Hs
		613239 ITA6_HUMAN (1-1130): 0: 1347: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		613234 ITA6_HUMAN (1-1130): 0: 1347: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		545210 ITA6_HUMAN (1-1130): 0: 1347: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436159 ITA6_HUMAN (1-1130): 0: 1347: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		613241 ITA6_HUMAN (1-1130): 0: 1347: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		613231 ITA6_HUMAN (1-1130): 0: 1347: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		613232 ITA6_HUMAN (1-1130): 0: 1347: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564413 ITA6_HUMAN (1-1130): 0: 1347: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120305 ITA6_HUMAN (1-1130): 0: 1347: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		639881 ITA3_HUMAN (7-1108): 0: 936: 34.72		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		639880 ITA3_HUMAN (7-1108): 0: 936: 34.72		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		639878 ITA3_HUMAN (7-1108): 0: 936: 34.72		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		419186 ITAV_HUMAN (21-1083): 0: 880: 25.14		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		419188 ITAV_HUMAN (21-1083): 0: 880: 25.14		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		419149 ITAV_HUMAN (21-1083): 0: 880: 25.14		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		419135 ITAV_HUMAN (21-1083): 0: 880: 25.14		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		419184 ITAV_HUMAN (21-1083): 0: 880: 25.14		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		419185 ITAV_HUMAN (21-1083): 0: 880: 25.14		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		419150 ITAV_HUMAN (21-1083): 0: 880: 25.14		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120277 ITAV_HUMAN (21-1083): 0: 880: 25.14		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98