HitPredict

Interactor 1: SFPQ (P23246)
Splicing factor, proline- and glutamine-rich (100 kDa DNA-pairing protein) (hPOMp100) (DNA-binding p52/p100 complex, 100 kDa subunit) (Polypyrimidine tract-binding protein-associated-splicing factor) (PSF) (PTB-associated-splicing factor)
Gene: SFPQ

Interactor 2: TNR6A (Q8NDV7)
Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa)
Gene: TNRC6A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28813667
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 707 Hs			1 1962
+	Hs
		516593 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Hs
		1242612 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		TNR6A_HUMAN (1-1962): 0: 896: 100.00
+	Hs
		1031469 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Hs
		516746 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		TNR6B_HUMAN (44-1944): 3.32e-153: 521: 33.57
+	Hs
		516700 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		TNR6C_HUMAN (35-1957): 8.26e-150: 513: 37.01
+	Dm
		597064 PABP_DROME (296-675): 1.13e-65: 230: 14.32		GAWKY_DROME (718-1889): 1.06e-50: 200: 20.88
+	Hs
		998651 PABP4_HUMAN (287-694): 8.34e-83: 277: 17.38		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		516595 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		KMT2C_HUMAN (1071-1765): 1.31e-13: 79.4: 10.54
+	Hs
		613431 SFPQ_HUMAN (1-707): 4.51e-74: 255: 100.00		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		516596 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		ARI1B_HUMAN (551-1540): 1.58e-09: 65.5: 8.99
+	Hs
		516480 PABP1_HUMAN (287-700): 1.59e-70: 243: 16.46		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		998729 NONO_HUMAN (265-707): 1.49e-70: 239: 56.98		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		1263569 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		RRBP1_HUMAN (329-778): 2.37e-09: 65.1: 13.30
+	Hs
		998921 PSPC1_HUMAN (230-707): 1.7e-60: 213: 51.96		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Hs
		999051 RBM4_HUMAN (298-436): 1.19e-40: 154: 27.97		EP300_HUMAN (789-1765): 6.73e-09: 63.6: 9.05
+	Mm
		1351630 PCLO_MOUSE (32-294): 4.8e-10: 65.7: 17.90		PCLO_MOUSE (19-1290): 1.41e-09: 66: 10.73
+	Dm
		113976 M9PB30_DROME (104-275): 2.02e-10: 66.8: 18.78		M9PB30_DROME (58-812): 9.58e-09: 63.2: 8.52