HitPredict

Interactor 1: A5YV76 (A5YV76)
Fatty acid synthase (EC 1.1.1.100) (EC 1.3.1.39) (EC 2.3.1.38) (EC 2.3.1.39) (EC 2.3.1.41) (EC 2.3.1.85) (EC 3.1.2.14) (EC 4.2.1.59)
Gene: FASN

Interactor 2: A5YV76 (A5YV76)
Fatty acid synthase (EC 1.1.1.100) (EC 1.3.1.39) (EC 2.3.1.38) (EC 2.3.1.39) (EC 2.3.1.41) (EC 2.3.1.85) (EC 3.1.2.14) (EC 4.2.1.59)
Gene: FASN

Species: Sus scrofa

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 18772430
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Acyl_transf_1~Acyl_transf_1, Acyl_transf_1~KAsynt_C_assoc, Acyl_transf_1~PP-binding, ADH_zinc_N_2~ADH_zinc_N_2, ADH_zinc_N_2~KR, KAsynt_C_assoc~KAsynt_C_assoc, KAsynt_C_assoc~ketoacyl-synt, KAsynt_C_assoc~Ketoacyl-synt_C, ketoacyl-synt~ketoacyl-synt, Ketoacyl-synt_C~ketoacyl-synt, PP-binding~ketoacyl-synt, Ketoacyl-synt_C~Ketoacyl-synt_C, KR~KR, Methyltransf_12~Methyltransf_12, PP-binding~PP-binding, PP-binding~Thioesterase, Thioesterase~Thioesterase
Common GO terms GO:0000166 - nucleotide binding
GO:0004312 - fatty acid synthase activity
GO:0004313 - [acyl-carrier-protein] S-acetyltransferase activity
GO:0004314 - [acyl-carrier-protein] S-malonyltransferase activity
GO:0004315 - 3-oxoacyl-[acyl-carrier-protein] synthase activity
and 7 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2512
Ss

1 2512
+ Hs
+ Rn
+ Bs
+ Ec
+ Mt
+ Ec
+ Sc
+ Mt
+ Pa
+ Hs
+ Hs
+ Hs
+ Sc
+ Sp
+ Ec
+ Mt
+ Bs

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Last updated: 15 Jul 2024