Interactor 1: MUTL (P23367)
DNA mismatch repair protein MutL
Gene: MUTL
Interactor 2: MUTS (P23909)
DNA mismatch repair protein MutS
Gene: MUTS
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.83 | 1.00 | 0.916 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29176613, 10734142, 10026220, 20080788, 19376855 |
| Identification Methods | affinity chromatography technology, experimental interaction detection, mass spectrometry study of hydrogen/deuterium exchange, pull down, adenylate cyclase complementation |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HATPase_c_3~MutS_II, HATPase_c_3~MutS_III, HATPase_c_3~MutS_V |
| Common GO terms | GO:0000018 - regulation of DNA recombination GO:0005524 - ATP binding GO:0006298 - mismatch repair GO:0016887 - ATP hydrolysis activity GO:0030983 - mismatched DNA binding and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
