Protein: SMD1
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (snRNP core protein D1)

Gene: SMD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 98
UniProt ID: Q02260

Gene Ontology (top 5):
GO:0000243 - commitment complex
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000395 - mRNA 5'-splice site recognition
GO:0000398 - mRNA splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817148

RSMB
Small nuclear ribonucleoprotein-associated protein B

7

5

Small-scale

0.960

High

1036187

RU2A
U2 small nuclear ribonucleoprotein A'

6

2

Small-scale

0.943

High

847821

SMD3
Small nuclear ribonucleoprotein Sm D3

5

8

Small-scale

0.922

High

780210

SN114
Pre-mRNA-splicing factor SNU114

4

2

High-throughput

0.896

High

625119

PRP9
Pre-mRNA-splicing factor PRP9

4

1

High-throughput

0.892

High

751775

PRP8
Pre-mRNA-splicing factor 8

4

1

Small-scale

0.892

High

820828

RUXG
Small nuclear ribonucleoprotein G

4

11

High-throughput

0.881

High

1036179

SMD2
Small nuclear ribonucleoprotein Sm D2

3

2

High-throughput

0.839

High

865279

LSM8
LSM2-LSM8 complex subunit LSM8

3

13

High-throughput

0.830

High

1027981

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

3

2

Small-scale

0.827

High

1036177

RU1C
U1 small nuclear ribonucleoprotein C

3

0

High-throughput

0.811

High

1036185

LUC7
Protein LUC7

3

0

High-throughput

0.796

High

1036169

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

2

1

High-throughput

0.789

High

758072

LOT5
Protein LOT5

3

0

Small-scale

0.782

High

795915

LSM2
LSM complex subunit LSM2

2

7

High-throughput

0.776

High

933130

RUXF
Small nuclear ribonucleoprotein F

2

3

High-throughput

0.776

High

1036191

RUXE
Small nuclear ribonucleoprotein E

2

2

High-throughput

0.776

High

744150

BRR2
Pre-mRNA-splicing helicase BRR2

7

5

Small-scale

0.741

High

818045

LSM4
LSM complex subunit LSM4

1

4

High-throughput

0.691

High

1036171

CEF1
Pre-mRNA-splicing factor CEF1

4

2

Small-scale

0.686

High

743548

RU1A
U1 small nuclear ribonucleoprotein A

5

0

Small-scale

0.684

High

1036188

CWC2
Pre-mRNA-splicing factor CWC2

3

2

High-throughput

0.667

High

918224

SNU71
U1 small nuclear ribonucleoprotein component SNU71

4

0

Small-scale

0.664

High

1036174

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

4

0

High-throughput

0.664

High

625041

PRP6
Pre-mRNA-splicing factor 6

3

3

High-throughput

0.662

High

739264

PRP21
Pre-mRNA-splicing factor PRP21

3

1

High-throughput

0.662

High

813369

PRP39
Pre-mRNA-processing factor 39

3

4

High-throughput

0.662

High

886349

PRP31
Pre-mRNA-processing factor 31

3

1

High-throughput

0.662

High

750292

PRP40
Pre-mRNA-processing protein PRP40

4

0

High-throughput

0.661

High

757520

NCBP1
Nuclear cap-binding protein complex subunit 1

4

0

High-throughput

0.661

High

739187

PRP19
Pre-mRNA-processing factor 19

3

3

Small-scale

0.650

High

1036166

CUS1
Cold sensitive U2 snRNA suppressor 1

3

1

High-throughput

0.650

High

1036195

BRR1
Pre-mRNA-splicing factor BRR1

1

0

High-throughput

0.631

High

945343

LSM3
LSM complex subunit LSM3

1

14

High-throughput

0.618

High

1025647

NAM8
Protein NAM8

3

0

Small-scale

0.613

High

1036183

PRP11
Pre-mRNA-splicing factor PRP11

2

1

High-throughput

0.601

High

1036165

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

Small-scale

0.586

High

1036175

SYF1
Pre-mRNA-splicing factor SYF1

2

3

Small-scale

0.584

High

1036190

CLF1
Pre-mRNA-splicing factor CLF1

2

3

Small-scale

0.584

High

1036193

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

1

Small-scale

0.584

High

1036170

CWC21
Pre-mRNA-splicing factor CWC21

2

0

Small-scale

0.559

High

1036186

NCBP2
Nuclear cap-binding protein subunit 2

2

0

High-throughput

0.559

High

735464

AAR2
A1 cistron-splicing factor AAR2

1

1

High-throughput

0.515

High

753010

XPOT
Exportin-T

1

1

High-throughput

0.508

High

664613

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

1

Small-scale

0.501

High

865387

RAV1
Regulator of V-ATPase in vacuolar membrane protein 1

1

0

High-throughput

0.486

High

917025

ARO8
Aromatic/aminoadipate aminotransferase 1

1

0

High-throughput

0.486

High

1036168

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.486

High

579924

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

627866

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

2

High-throughput

0.479

High

638014

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

1

3

High-throughput

0.479

High

682362

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.479

High

741070

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

829950

PRP17
Pre-mRNA-processing factor 17

1

4

High-throughput

0.479

High

892775

SF3B1
U2 snRNP component HSH155

1

2

High-throughput

0.479

High

1036173

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

6

High-throughput

0.479

High

1036176

RSE1
Pre-mRNA-splicing factor RSE1

1

1

High-throughput

0.479

High

1036192

PRP46
Pre-mRNA-splicing factor PRP46

1

3

High-throughput

0.479

High

1036167

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.460

High

603096

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

638074

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

672067

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

700133

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.458

High

702271

YJU2
Splicing factor YJU2

1

0

High-throughput

0.458

High

707945

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

738905

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.458

High

780848

MUD2
Splicing factor MUD2

1

0

Small-scale

0.458

High

781580

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

796454

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.458

High

797317

SP381
Pre-mRNA-splicing factor SPP381

1

0

High-throughput

0.458

High

797683

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

812583

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

918430

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

919213

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

919724

CWC22
Pre-mRNA-splicing factor CWC22

1

0

High-throughput

0.458

High

1026944

PRP38
Pre-mRNA-splicing factor 38

1

0

High-throughput

0.458

High

1036172

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

1036178

SN309
Pre-mRNA-splicing factor SNT309

1

0

High-throughput

0.458

High

1036181

DIB1
Spliceosomal protein DIB1

1

0

High-throughput

0.458

High

1036182

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.458

High

1036184

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

1036189

BBP
Branchpoint-bridging protein

1

0

Small-scale

0.458

High

524890

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527468

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

545955

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

816360

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.445

High

819558

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

785961

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.437

High

824771

MLP2
Protein MLP2

1

1

High-throughput

0.437

High

923932

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.426

High

924047

JJJ1
J protein JJJ1

1

0

High-throughput

0.426

High

1036180

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.426

High

924933

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.269

Low

602083

SAC7
GTPase-activating protein SAC7

1

0

High-throughput

0.265

Low

758015

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.265

Low

796248

QDR3
Quinidine resistance protein 3

1

0

High-throughput

0.265

Low

1036194

SEC39
Protein transport protein SEC39

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025