HitPredict

Interactor 1: JAK1 (P23458)
Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
Gene: JAK1

Interactor 2: JAK1 (P23458)
Tyrosine-protein kinase JAK1 (EC 2.7.10.2) (Janus kinase 1) (JAK-1)
Gene: JAK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 1.00 0.888

The method score is based on:

Property Details
Experiments 32001089, 8041779, 8790359, 15173123
Identification Methods enzymatic study, in-gel kinase assay
Interaction Type direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains FERM_F1~FERM_F1, FERM_F1~FERM_F2, FERM_F1~Jak1_Phl, FERM_F2~FERM_F2, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0004713 - protein tyrosine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005131 - growth hormone receptor binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 34 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024