HitPredict

Interactor 1: ATF3 (P18847)
Cyclic AMP-dependent transcription factor ATF-3 (cAMP-dependent transcription factor ATF-3) (Activating transcription factor 3)
Gene: ATF3

Interactor 2: RBTN1 (P25800)
Rhombotin-1 (Cysteine-rich protein TTG-1) (LIM domain only protein 1) (LMO-1) (T-cell translocation protein 1)
Gene: LMO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 181 Hs			1 156
+	Hs
		583570 ATF2_HUMAN (17-168): 1.46e-23: 98.4: 21.05		LHX8_HUMAN (14-143): 5.22e-48: 160: 40.00
+	Hs
		584106 FOSL2_HUMAN (54-164): 8.4e-22: 91.8: 37.84		LHX8_HUMAN (14-143): 5.22e-48: 160: 40.00
+	Hs
		1232333 Q6FG41_HUMAN (14-175): 3.48e-21: 90.6: 20.34		LMO3_HUMAN (13-156): 5.12e-39: 130: 89.58
+	Hs
		370731 FOS_HUMAN (14-175): 3.48e-21: 90.6: 20.34		LMO3_HUMAN (13-156): 5.12e-39: 130: 89.58
+	Dm
		1344928 Q8SZT1_DROME (23-146): 1.18e-20: 90.3: 21.77		Q9VTW3_DROME (24-144): 3.98e-22: 93.2: 37.19
+	Dm
		1217090 Q5U8V5_DROME (23-146): 2.61e-21: 89.9: 21.77		Q9VTW3_DROME (24-144): 3.98e-22: 93.2: 37.19
+	Hs
		607135 CEBPB_HUMAN (55-148): 2.81e-20: 88: 23.40		PDLI7_HUMAN (83-154): 3.1e-11: 61.9: 24.66
+	Hs
		253012 CREB5_HUMAN (40-163): 2.55e-21: 91.8: 24.00		LMX1B_HUMAN (88-152): 1.45e-09: 57.3: 21.21