HitPredict

Interactor 1: H2B1O (P23527)
Histone H2B type 1-O (H2B-clustered histone 17) (Histone H2B.2) (Histone H2B.n) (H2B/n)
Gene: H2BC17

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31300519
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 581
+	Hs
		1129846 H2B2F_HUMAN (1-126): 1.28e-55: 171: 98.41		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1087382 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1274430 H2B1H_HUMAN (1-126): 3.39e-55: 169: 99.21		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1307124 H2B1M_HUMAN (1-126): 3.31e-55: 169: 95.24		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		420877 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Mm
		682111 H2B2B_MOUSE (1-126): 1.28e-55: 171: 98.41		AKT1_MOUSE (115-573): 2.96e-119: 363: 13.51
+	Mm
		682113 H2B1C_MOUSE (1-126): 7.88e-55: 169: 98.41		AKT1_MOUSE (115-573): 2.96e-119: 363: 13.51
+	Hs
		617926 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		420806 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		681878 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		617927 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		AKT2_HUMAN (115-573): 1.5e-117: 358: 12.66
+	Hs
		681686 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		420807 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		AKT2_HUMAN (115-573): 1.5e-117: 358: 12.66
+	Hs
		682181 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		AKT2_HUMAN (115-573): 1.5e-117: 358: 12.66
+	Hs
		682137 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		AKT2_HUMAN (115-573): 1.5e-117: 358: 12.66
+	Hs
		568756 H2B1H_HUMAN (1-126): 3.39e-55: 169: 99.21		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		617936 H2B1O_HUMAN (1-126): 1.76e-55: 170: 100.00		KS6A3_HUMAN (154-555): 2.08e-92: 301: 16.59
+	Hs
		420815 H2B1J_HUMAN (1-126): 5.49e-55: 169: 98.41		KS6A3_HUMAN (154-555): 2.08e-92: 301: 16.59
+	Hs
		850663 H2B2E_HUMAN (1-126): 4.92e-55: 169: 99.21		KS6A3_HUMAN (154-555): 2.08e-92: 301: 16.59
+	Hs
		707559 H2B1B_HUMAN (1-126): 1.21e-54: 168: 97.62		KS6A3_HUMAN (154-555): 2.08e-92: 301: 16.59