Protein: IRA2
Inhibitory regulator protein IRA2

Gene: IRA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 49
UniProt ID: P19158

Gene Ontology (top 5):
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376211

RAS2
Ras-like protein 2

2

20

Small-scale

0.778

High

617969

IRA1
Inhibitory regulator protein IRA1

2

14

Small-scale

0.754

High

618963

GPB1
Guanine nucleotide-binding protein subunit beta 1

3

3

Small-scale

0.670

High

571341

CPYI
Carboxypeptidase Y inhibitor

2

1

Small-scale

0.633

High

618950

GPB2
Guanine nucleotide-binding protein subunit beta 2

2

3

Small-scale

0.584

High

454698

KAPR
cAMP-dependent protein kinase regulatory subunit

1

5

Small-scale

0.561

High

618941

HRR25
Casein kinase I homolog HRR25

1

12

High-throughput

0.536

High

618948

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

10

High-throughput

0.536

High

618956

MMS2
Ubiquitin-conjugating enzyme variant MMS2

1

0

High-throughput

0.513

High

437874

KAPC
cAMP-dependent protein kinase type 3

1

9

Small-scale

0.501

High

441028

KAPA
cAMP-dependent protein kinase type 1

1

9

Small-scale

0.501

High

441321

KAPB
cAMP-dependent protein kinase type 2

1

8

Small-scale

0.501

High

618964

RIO1
Serine/threonine-protein kinase RIO1

1

3

Small-scale

0.481

High

366919

ATPB
ATP synthase subunit beta, mitochondrial

1

1

Small-scale

0.479

High

415101

ADT1
ADP,ATP carrier protein 1

1

2

Small-scale

0.479

High

509385

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

5

Small-scale

0.479

High

510173

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.479

High

523004

HSP71
Heat shock protein SSA1

1

10

Small-scale

0.479

High

597029

BIP
Endoplasmic reticulum chaperone BiP

1

6

Small-scale

0.479

High

618937

TRX2
Thioredoxin-2

1

1

High-throughput

0.479

High

618942

HSP7F
Heat shock protein homolog SSE1

1

14

Small-scale

0.479

High

618944

GBLP
Small ribosomal subunit protein RACK1

1

11

Small-scale

0.479

High

618951

PHB1
Prohibitin-1

1

3

Small-scale

0.479

High

618954

RIM15
Serine/threonine-protein kinase RIM15

1

12

Small-scale

0.479

High

618958

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

Small-scale

0.479

High

618959

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.479

High

618960

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

618962

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.479

High

364917

KPYK1
Pyruvate kinase 1

1

0

Small-scale

0.458

High

365555

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.458

High

572509

ALF
Fructose-bisphosphate aldolase

1

0

Small-scale

0.458

High

618938

RNQ1
[PIN+] prion protein RNQ1

1

0

Small-scale

0.458

High

618939

PYRD
Dihydroorotate dehydrogenase

1

0

Small-scale

0.458

High

618943

GPX1
Glutathione peroxidase-like peroxiredoxin 1

1

0

High-throughput

0.458

High

618946

SYG
Glycine--tRNA ligase 1, mitochondrial

1

0

Small-scale

0.458

High

618952

MPG1
Mannose-1-phosphate guanyltransferase

1

0

Small-scale

0.458

High

618955

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

618961

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

525877

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

578810

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.445

High

603403

VATA
V-type proton ATPase catalytic subunit A

1

3

Small-scale

0.437

High

618940

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

618945

ANM1
Protein arginine N-methyltransferase 1

1

3

High-throughput

0.437

High

618947

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

618936

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

618949

TCPD
T-complex protein 1 subunit delta

1

3

High-throughput

0.407

High

618957

IPI3
Pre-rRNA-processing protein IPI3

1

4

High-throughput

0.407

High

618953

GZF3
Protein GZF3

1

0

High-throughput

0.282

High

511062

ERR1
Enolase-related protein 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025