HitPredict

Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	27684187, 31501420, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 166 Hs			1 504
+	Hs
		125160 COF1_HUMAN (1-166): 4.46e-72: 215: 100.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		618179 COF1_HUMAN (1-166): 4.46e-72: 215: 100.00		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		808552 TWF1_HUMAN (3-157): 1.01e-34: 126: 21.52		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		1152316 TWF2_HUMAN (3-151): 2.29e-29: 111: 17.11		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		618191 COF1_HUMAN (1-166): 4.46e-72: 215: 100.00		HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79
+	Dm
		799746 CADF_DROME (1-153): 1.89e-36: 124: 29.01		YAP1_DROME (52-268): 1.16e-44: 163: 29.25