Protein: ARFP2
Arfaptin-2 (ADP-ribosylation factor-interacting protein 2) (Partner of RAC1) (POR1)

Gene: ARFP2, ARFIP2
Organism: Homo sapiens
Interactions: 98
UniProt ID: P53365

Gene Ontology (top 5):
GO:0000423 - mitophagy
GO:0001726 - ruffle
GO:0005525 - GTP binding
GO:0005543 - phospholipid binding
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

920554

RAC1
Ras-related C3 botulinum toxin substrate 1

8

8

Small-scale

0.970

High

920548

ARFP1
Arfaptin-1

6

11

High-throughput

0.946

High

920547

ARFP2
Arfaptin-2

6

11

Small-scale

0.941

High

920555

ARF1
ADP-ribosylation factor 1

4

10

Small-scale

0.892

High

827150

ARL1
ADP-ribosylation factor-like protein 1

3

13

Small-scale

0.854

High

920556

ARF5
ADP-ribosylation factor 5

3

10

Small-scale

0.849

High

920551

ARF3
ADP-ribosylation factor 3

3

10

Small-scale

0.839

High

920552

ARF6
ADP-ribosylation factor 6

2

11

Small-scale

0.825

High

580950

RAC2
Ras-related C3 botulinum toxin substrate 2

2

8

High-throughput

0.783

High

920550

RAC3
Ras-related C3 botulinum toxin substrate 3

2

8

High-throughput

0.783

High

920586

RND1
Rho-related GTP-binding protein Rho6

2

10

High-throughput

0.783

High

618013

K1C15
Keratin, type I cytoskeletal 15

3

5

High-throughput

0.675

High

920571

ATRAP
Type-1 angiotensin II receptor-associated protein

4

0

High-throughput

0.673

High

920609

SHLB1
Endophilin-B1

3

3

High-throughput

0.660

High

332626

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.638

High

920603

DUS22
Dual specificity protein phosphatase 22

2

1

High-throughput

0.628

High

920562

CENPR
Centromere protein R

2

0

High-throughput

0.618

High

612175

ARF4
ADP-ribosylation factor 4

1

10

High-throughput

0.618

High

630737

RAB4A
Ras-related protein Rab-4A

1

7

High-throughput

0.618

High

901142

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.618

High

920553

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.618

High

140193

SDCB1
Syntenin-1

2

3

High-throughput

0.606

High

178746

SCAM1
Secretory carrier-associated membrane protein 1

2

2

High-throughput

0.606

High

476287

K1C16
Keratin, type I cytoskeletal 16

2

5

High-throughput

0.606

High

719419

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

2

1

High-throughput

0.606

High

920559

REL
Proto-oncogene c-Rel

2

2

High-throughput

0.606

High

920560

PLP2
Proteolipid protein 2

2

2

High-throughput

0.606

High

920570

BL1S2
Biogenesis of lysosome-related organelles complex 1 subunit 2

2

1

High-throughput

0.606

High

920581

SCAM5
Secretory carrier-associated membrane protein 5

2

2

High-throughput

0.606

High

920582

LNX1
E3 ubiquitin-protein ligase LNX

2

3

High-throughput

0.606

High

920595

PKNX2
Homeobox protein PKNOX2

2

3

High-throughput

0.606

High

920608

NDRG4
Protein NDRG4

2

3

High-throughput

0.606

High

920596

CEP63
Centrosomal protein of 63 kDa

2

0

High-throughput

0.601

High

920566

NF2L2
Nuclear factor erythroid 2-related factor 2

1

1

Small-scale

0.582

High

225474

CYH3
Cytohesin-3

2

0

High-throughput

0.580

High

789082

NUP62
Nuclear pore glycoprotein p62

2

0

High-throughput

0.580

High

885154

TTPA
Alpha-tocopherol transfer protein

2

0

High-throughput

0.580

High

920561

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.580

High

920567

GSG1
Germ cell-specific gene 1 protein

2

0

High-throughput

0.580

High

920598

SMG9
Nonsense-mediated mRNA decay factor SMG9

2

0

High-throughput

0.580

High

920599

NRDE2
Nuclear exosome regulator NRDE2

2

0

High-throughput

0.580

High

920600

DMAP1
DNA methyltransferase 1-associated protein 1

2

0

High-throughput

0.580

High

169482

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

High-throughput

0.573

High

920597

TRI54
Tripartite motif-containing protein 54

1

5

High-throughput

0.573

High

920565

ITSN1
Intersectin-1

1

2

High-throughput

0.568

High

51405

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

5

High-throughput

0.553

High

469473

SYPH
Synaptophysin

2

1

High-throughput

0.553

High

920557

REEP5
Receptor expression-enhancing protein 5

2

1

High-throughput

0.553

High

920589

MID49
Mitochondrial dynamics protein MID49

2

1

High-throughput

0.553

High

920591

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

1

High-throughput

0.553

High

920601

MID51
Mitochondrial dynamics protein MIEF1

2

1

High-throughput

0.553

High

842695

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

3

Small-scale

0.552

High

920590

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.549

High

625262

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.536

High

920579

USBP1
Harmonin-binding protein USHBP1

1

1

High-throughput

0.523

High

920585

ING5
Inhibitor of growth protein 5

1

2

High-throughput

0.523

High

920564

LY6D
Lymphocyte antigen 6D

1

0

High-throughput

0.518

High

920592

DTBP1
Dysbindin

1

0

High-throughput

0.518

High

561965

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.515

High

843406

HD
Huntingtin

1

1

High-throughput

0.515

High

692673

CALL3
Calmodulin-like protein 3

1

0

High-throughput

0.513

High

813044

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.513

High

920574

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

0

High-throughput

0.513

High

920578

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.513

High

920607

ING1
Inhibitor of growth protein 1

1

2

High-throughput

0.489

High

155095

SOCS2
Suppressor of cytokine signaling 2

1

2

High-throughput

0.481

High

728128

AKT1
RAC-alpha serine/threonine-protein kinase

1

6

Small-scale

0.481

High

421768

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

225973

STX6
Syntaxin-6

1

1

High-throughput

0.479

High

327205

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.479

High

555972

CADH1
Cadherin-1

1

1

High-throughput

0.479

High

920549

ATX3
Ataxin-3

1

1

Small-scale

0.479

High

920569

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

920573

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.479

High

920583

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

920593

BICD1
Protein bicaudal D homolog 1

1

1

High-throughput

0.479

High

280558

PR40A
Pre-mRNA-processing factor 40 homolog A

1

2

High-throughput

0.470

High

920588

Q96AL5
PBX3 protein

1

4

High-throughput

0.470

High

827718

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.460

High

920563

SNX1
Sorting nexin-1

1

0

High-throughput

0.460

High

920558

EWS
RNA-binding protein EWS

1

0

High-throughput

0.458

High

823929

PBX3
Pre-B-cell leukemia transcription factor 3

1

4

High-throughput

0.439

High

920602

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

695007

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

920575

TMM17
Transmembrane protein 17

1

1

High-throughput

0.437

High

920604

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.437

High

920605

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.437

High

920587

MAL2
Protein MAL2

3

0

High-throughput

0.352

High

908501

CDR1
Cerebellar degeneration-related antigen 1

2

0

High-throughput

0.316

High

920572

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

0

High-throughput

0.316

High

920580

FADS6
Fatty acid desaturase 6

2

0

High-throughput

0.316

High

920584

T255B
Transmembrane protein 255B

2

0

High-throughput

0.316

High

920606

CS025
UPF0449 protein C19orf25

2

0

High-throughput

0.316

High

920568

TMM31
Transmembrane protein 31

1

0

High-throughput

0.279

Low

920576

XYLT1
Xylosyltransferase 1

1

0

High-throughput

0.279

Low

920577

CCAR1
Cell division cycle and apoptosis regulator protein 1

1

0

High-throughput

0.279

Low

920594

RUSF1
RUS family member 1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025