Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1

Interactor 2: LIMK2 (P53671)
LIM domain kinase 2 (LIMK-2) (EC 2.7.11.1)
Gene: LIMK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.768

The method score is based on:

Property Details
Experiments 23082153, 10436159
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cofilin_ADF~PK_Tyr_Ser-Thr
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0030036 - actin cytoskeleton organization
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 166
Hs

1 638
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024