HitPredict

Interactor 1: PP2A2 (P23595)
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit (EC 3.1.3.16)
Gene: PPH22

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	19536198, 23332755
Identification Methods	affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 377 Sc			1 613
+	Sc
		510318 PP2A2_YEAST (1-377): 0: 582: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		618777 PP2A1_YEAST (1-377): 0: 562: 88.06		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510317 PP2A1_YEAST (1-377): 0: 562: 88.06		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		594327 PP11_YEAST (79-377): 1.14e-130: 378: 54.75		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510236 PP11_YEAST (79-377): 1.14e-130: 378: 54.75		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		503837 PP2AB_HUMAN (70-377): 0: 539: 74.35		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		503863 PP2AA_HUMAN (70-377): 0: 538: 74.68		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		503566 PP1G_HUMAN (66-374): 0: 527: 43.55		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		503821 PP1A_HUMAN (65-364): 0: 524: 44.85		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		713915 PP1G_HUMAN (66-374): 0: 527: 43.55		HS71L_HUMAN (5-612): 0: 893: 59.51
+	Hs
		713936 PP1A_HUMAN (65-364): 0: 524: 44.85		HS71L_HUMAN (5-612): 0: 893: 59.51
+	Hs
		905943 PP1A_HUMAN (65-364): 0: 524: 44.85		Q53FA3_HUMAN (5-612): 0: 893: 59.67
+	Mm
		571852 PP1G_MOUSE (66-374): 0: 527: 43.55		HS71B_MOUSE (5-611): 0: 889: 59.61
+	Hs
		737670 PP1G_HUMAN (66-374): 0: 527: 43.55		HSP72_HUMAN (4-612): 0: 888: 60.13
+	Mm
		571849 PP1A_MOUSE (65-364): 0: 525: 45.18		HS71B_MOUSE (5-611): 0: 889: 59.61
+	Sc
		449917 PP2A2_YEAST (1-377): 0: 582: 100.00		HSP73_YEAST (9-611): 0: 677: 60.66
+	Sc
		449904 PP11_YEAST (79-377): 1.14e-130: 378: 54.75		HSP73_YEAST (9-611): 0: 677: 60.66