Interactor 1: IRF8 (P23611)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (ICSBP)
Gene: IRF8

Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 16093364, 21731497
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0006909 - phagocytosis
GO:0009617 - response to bacterium
GO:0032729 - positive regulation of type II interferon production
GO:0032735 - positive regulation of interleukin-12 production
GO:0043065 - positive regulation of apoptotic process
and 3 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 424
Mm

1 835
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs

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Last updated: 15 Jul 2024