HitPredict

Interactor 1: FUSED (P23647)
Serine/threonine-protein kinase fused (EC 2.7.11.1)
Gene: fu

Interactor 2: Q9VG38 (Q9VG38)
Suppressor of fused homolog
Gene: Su(fu)

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	21844892, 10825151, 14636583, 26271100, 9601642, 14611647, 15710747
Identification Methods	enzymatic study, pull down, affinity chromatography technology, two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0045879 - negative regulation of smoothened signaling pathway
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 805 Dm			1 468
+	Dm
		619785 FUSED_DROME (1-805): 0: 922: 100.00		Q27279_DROME (1-468): 0: 836: 98.93
+	Hs
		1345008 STK36_HUMAN (1-286): 3.86e-119: 391: 51.21		SUFU_HUMAN (15-466): 0: 671: 37.37