HitPredict

Interactor 1: GRIA2 (P23819)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: AGAP2 (Q3UHD9)
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP-2) (Centaurin-gamma-1) (Cnt-g1) (Phosphatidylinositol 3-kinase enhancer) (PIKE)
Gene: AGAP2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	21847098, 28706196
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019901 - protein kinase binding GO:0030425 - dendrite GO:0035255 - ionotropic glutamate receptor binding GO:0044877 - protein-containing complex binding GO:0098978 - glutamatergic synapse and 1 others more... GO:1905430 - cellular response to glycine
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 883 Mm			1 1186
+	Rn
		585178 GRIA2_RAT (1-883): 0: 926: 99.89		AGAP2_RAT (1-1186): 0: 1019: 99.07
+	Hs
		786742 GRIA2_HUMAN (1-883): 0: 928: 99.66		AGAP2_HUMAN (1-1147): 0: 987: 94.10
+	Mm
		620886 GRIA1_MOUSE (4-862): 0: 859: 69.05		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Rn
		585155 GRIA1_RAT (4-862): 0: 862: 69.98		AGAP2_RAT (1-1186): 0: 1019: 99.07
+	Mm
		100188 F6YNQ1_MOUSE (73-862): 0: 811: 72.24		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		723576 NMDZ1_MOUSE (1-868): 0: 575: 22.29		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		963721 NMDE2_MOUSE (28-845): 0: 570: 22.37		AGAP2_MOUSE (1-1186): 0: 1024: 100.00
+	Mm
		723556 NMDZ1_MOUSE (1-868): 0: 575: 22.29		RAP1A_MOUSE (398-567): 1.81e-70: 235: 23.03
+	Mm
		919690 NMDE2_MOUSE (28-845): 0: 570: 22.37		RAP1A_MOUSE (398-567): 1.81e-70: 235: 23.03