Interactor 1: TNNI3 (P19429)
Troponin I, cardiac muscle (Cardiac troponin I)
Gene: TNNI3
Interactor 2: TNNC1 (P63316)
Troponin C, slow skeletal and cardiac muscles (TN-C)
Gene: TNNC1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.93 | 1.00 | 0.968 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18986304, 15134451, 15049709, 29997244, 33961781, 12939162, 12060657, 12122471, 7957210 |
| Identification Methods | pull down, fluorescent resonance energy transfer, affinity chromatography technology, x-ray crystallography, unspecified method, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EF-hand_7~Troponin, EF-hand_8~Troponin |
| Common GO terms | GO:0003009 - skeletal muscle contraction GO:0005829 - cytosol GO:0005861 - troponin complex GO:0030017 - sarcomere GO:0030049 - muscle filament sliding and 6 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
