Protein: TNNI3
Troponin I, cardiac muscle (Cardiac troponin I)

Gene: TNNI3
Organism: Homo sapiens
Interactions: 25
UniProt ID: P19429

Gene Ontology (top 5):
GO:0001570 - vasculogenesis
GO:0001980 - regulation of systemic arterial blood pressure by ischemic conditions
GO:0003009 - skeletal muscle contraction
GO:0003779 - actin binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

622497

TNNC1
Troponin C, slow skeletal and cardiac muscles

9

8

Small-scale

0.968

High

387095

TNNC2
Troponin C, skeletal muscle

2

8

High-throughput

0.817

High

622494

TNNT2
Troponin T, cardiac muscle

2

4

Small-scale

0.778

High

66480

RASFA
Ras association domain-containing protein 10

2

0

High-throughput

0.580

High

622499

PKD2
Polycystin-2

1

2

Small-scale

0.573

High

622510

PK2L1
Polycystin-2-like protein 1

1

2

Small-scale

0.573

High

622506

TRI63
E3 ubiquitin-protein ligase TRIM63

2

6

Small-scale

0.552

High

622511

RCAN3
Calcipressin-3

1

0

Small-scale

0.543

High

622493

HGFL
Hepatocyte growth factor-like protein

1

1

Small-scale

0.523

High

231675

PEX1
Peroxisomal ATPase PEX1

1

0

High-throughput

0.493

High

301333

WFS1
Wolframin

1

0

High-throughput

0.493

High

622496

PRS8
26S proteasome regulatory subunit 8

1

1

High-throughput

0.481

High

622501

HSPB2
Heat shock protein beta-2

1

5

High-throughput

0.481

High

622505

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

622498

SOX4
Transcription factor SOX-4

1

0

Small-scale

0.460

High

622492

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

Small-scale

0.457

High

622509

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

1

High-throughput

0.457

High

622508

TRI55
Tripartite motif-containing protein 55

1

6

High-throughput

0.439

High

622503

MYOME
Myomegalin

1

1

Small-scale

0.417

High

622502

TNI3K
Serine/threonine-protein kinase TNNI3K

2

0

Small-scale

0.329

High

420241

IFNA4
Interferon alpha-4

2

0

High-throughput

0.319

High

622500

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.269

Low

622507

LYST
Lysosomal-trafficking regulator

1

0

Small-scale

0.251

Low

622495

ATRX
Transcriptional regulator ATRX

1

0

High-throughput

0.249

Low

622504

PAQR2
Adiponectin receptor protein 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025