HitPredict

Interactor 1: CCND1 (P24385)
G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)
Gene: CCND1

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	33854235, 33854239
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043524 - negative regulation of neuron apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 295 Hs			1 1298
+	Hs
		673104 CCND2_HUMAN (3-295): 5.15e-81: 248: 61.22		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		673166 CCND3_HUMAN (3-295): 2.73e-76: 236: 51.69		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		622420 CCND1_HUMAN (1-295): 1.33e-74: 232: 100.00		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39
+	Hs
		622505 CCND1_HUMAN (1-295): 1.33e-74: 232: 100.00		SNR40_HUMAN (45-329): 6.16e-55: 197: 11.75
+	Hs
		622391 CCND1_HUMAN (1-295): 1.33e-74: 232: 100.00		LIS1_HUMAN (123-346): 3.66e-35: 141: 11.45
+	Hs
		331644 CCNE2_HUMAN (44-188): 8.58e-19: 87.4: 32.65		FBXW7_HUMAN (164-329): 5.74e-18: 91.8: 9.58
+	Hs
		624603 CCNE1_HUMAN (25-208): 7.3e-18: 84.7: 28.50		FBXW7_HUMAN (164-329): 5.74e-18: 91.8: 9.58