HitPredict

Interactor 1: CCND1 (P24385)
G1/S-specific cyclin-D1 (B-cell lymphoma 1 protein) (BCL-1) (BCL-1 oncogene) (PRAD1 oncogene)
Gene: CCND1

Interactor 2: HERC5 (Q9UII4)
E3 ISG15--protein ligase HERC5 (EC 2.3.2.-) (Cyclin-E-binding protein 1) (HECT domain and RCC1-like domain-containing protein 5)
Gene: HERC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10581175
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 295 Hs			1 1024
+	Hs
		538622 CCNB1_HUMAN (5-282): 3.94e-89: 273: 20.64		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		590232 CCNA2_HUMAN (3-286): 6.9e-81: 252: 24.48		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		673174 CCND3_HUMAN (3-295): 2.73e-76: 236: 51.69		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		624617 CCNE1_HUMAN (25-208): 7.3e-18: 84.7: 28.50		HERC5_HUMAN (1-1024): 0: 1123: 100.00
+	Hs
		943807 CCNA1_HUMAN (7-281): 7.64e-89: 274: 23.91		HECW2_HUMAN (534-1024): 2.54e-153: 496: 23.43