HitPredict

Interactor 1: EDNRB (P24530)
Endothelin receptor type B (ET-B) (ET-BR) (Endothelin receptor non-selective type)
Gene: EDNRB

Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 442 Hs			1 3056
+	Hs
		895616 CXCR4_HUMAN (95-401): 9.47e-78: 247: 21.82		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		723037 OPRM_HUMAN (34-433): 1.41e-73: 238: 19.75		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		723296 APJ_HUMAN (82-440): 3.59e-69: 226: 21.94		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		824699 NPY2R_HUMAN (71-403): 1.47e-68: 224: 23.05		ATM_HUMAN (1-3056): 0: 3806: 100.00
+	Hs
		723038 OPRM_HUMAN (34-433): 1.41e-73: 238: 19.75		ATR_HUMAN (1223-3056): 0: 1214: 20.34
+	Hs
		787434 CXCR4_HUMAN (95-401): 9.47e-78: 247: 21.82		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		723279 APJ_HUMAN (82-440): 3.59e-69: 226: 21.94		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		787417 NPY2R_HUMAN (71-403): 1.47e-68: 224: 23.05		MTOR_HUMAN (1846-3055): 0: 843: 16.65
+	Hs
		429015 ADRB2_HUMAN (72-409): 1.45e-72: 235: 19.06		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		666304 NK3R_HUMAN (26-434): 1.71e-68: 226: 18.53		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		824698 NPY2R_HUMAN (71-403): 1.47e-68: 224: 23.05		PRKDC_HUMAN (2005-3056): 6.86e-155: 545: 17.20
+	Hs
		787363 CXCR4_HUMAN (95-401): 9.47e-78: 247: 21.82		PK3CB_HUMAN (2385-3011): 9.82e-99: 348: 13.76
+	Hs
		822537 CXCR4_HUMAN (95-401): 9.47e-78: 247: 21.82		PK3CG_HUMAN (2437-2965): 4.25e-88: 316: 16.14
+	Mm
		936867 CXCR4_MOUSE (75-411): 1.52e-78: 249: 21.30		PK3CG_MOUSE (2446-2965): 4.69e-87: 313: 16.04