Protein: APOB
Apolipoprotein B-100 (Apo B-100) [Cleaved into: Apolipoprotein B-48 (Apo B-48)]

Gene: APOB
Organism: Homo sapiens
Interactions: 148
UniProt ID: P04114

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0005543 - phospholipid binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376443

MTP
Microsomal triglyceride transfer protein large subunit

3

7

Small-scale

0.859

High

376523

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

4

0

Small-scale

0.670

High

376442

TERA
Transitional endoplasmic reticulum ATPase

3

0

Small-scale

0.638

High

376466

TM41B
Transmembrane protein 41B

3

0

High-throughput

0.622

High

376404

APOB
Apolipoprotein B-100

1

7

Small-scale

0.618

High

376415

PDIA4
Protein disulfide-isomerase A4

1

2

Small-scale

0.618

High

337740

EGFR
Epidermal growth factor receptor

2

1

High-throughput

0.611

High

361291

APOA1
Apolipoprotein A-I

2

2

Small-scale

0.611

High

376504

P2Y12
P2Y purinoceptor 12

2

2

High-throughput

0.611

High

376406

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.602

High

376455

NTCP7
Sodium/bile acid cotransporter 7

2

0

High-throughput

0.602

High

376469

ZFY27
Protrudin

2

0

High-throughput

0.602

High

376487

SPX3
Sugar phosphate exchanger 3

2

0

High-throughput

0.602

High

376493

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

0

High-throughput

0.602

High

376502

YIPF3
Protein YIPF3

2

0

High-throughput

0.602

High

376505

ZDH11
Palmitoyltransferase ZDHHC11

2

0

High-throughput

0.602

High

376513

NSMA2
Sphingomyelin phosphodiesterase 3

2

0

High-throughput

0.602

High

224264

RAD21
Double-strand-break repair protein rad21 homolog

2

0

High-throughput

0.585

High

376496

DERL1
Derlin-1

2

0

Small-scale

0.585

High

376428

CALX
Calnexin

2

1

Small-scale

0.584

High

226227

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

376489

FAF2
FAS-associated factor 2

2

0

Small-scale

0.559

High

376467

TM128
Transmembrane protein 128

2

1

High-throughput

0.558

High

351036

LDLR
Low-density lipoprotein receptor

1

2

Small-scale

0.536

High

64150

IFM5
Interferon-induced transmembrane protein 5

1

1

High-throughput

0.536

High

198364

KLK10
Kallikrein-10

1

2

High-throughput

0.536

High

376440

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.536

High

376453

VMAT2
Synaptic vesicular amine transporter

1

1

High-throughput

0.536

High

376476

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

Small-scale

0.536

High

376490

ARX
Homeobox protein ARX

1

2

High-throughput

0.536

High

376475

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.515

High

126342

MATN2
Matrilin-2

1

0

High-throughput

0.513

High

134351

ACKR2
Atypical chemokine receptor 2

1

0

High-throughput

0.513

High

168490

SCAM2
Secretory carrier-associated membrane protein 2

1

0

High-throughput

0.513

High

173418

RER1
Protein RER1

1

0

High-throughput

0.513

High

206453

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.513

High

213099

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

335336

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.513

High

376411

BIP
Endoplasmic reticulum chaperone BiP

1

0

Small-scale

0.513

High

376413

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.513

High

376421

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

0

High-throughput

0.513

High

376424

NK1R
Substance-P receptor

1

0

High-throughput

0.513

High

376425

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.513

High

376432

MYH9
Myosin-9

1

0

High-throughput

0.513

High

376435

P2RY2
P2Y purinoceptor 2

1

0

High-throughput

0.513

High

376436

S19A1
Reduced folate transporter

1

0

High-throughput

0.513

High

376438

CRKL
Crk-like protein

1

0

High-throughput

0.513

High

376454

MZT1
Mitotic-spindle organizing protein 1

1

0

High-throughput

0.513

High

376457

MALL
MAL-like protein

1

0

High-throughput

0.513

High

376465

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.513

High

376473

GOT1A
Vesicle transport protein GOT1A

1

0

High-throughput

0.513

High

376477

CIR1
Corepressor interacting with RBPJ 1

1

0

High-throughput

0.513

High

376488

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.513

High

376494

SELS
Selenoprotein S

1

0

Small-scale

0.513

High

376495

TM208
Transmembrane protein 208

1

0

High-throughput

0.513

High

376506

CERS4
Ceramide synthase 4

1

0

High-throughput

0.513

High

376507

ELOV3
Very long chain fatty acid elongase 3

1

0

High-throughput

0.513

High

376508

ANLN
Anillin

1

0

High-throughput

0.513

High

376511

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

0

High-throughput

0.513

High

376512

GP173
Probable G-protein coupled receptor 173

1

0

High-throughput

0.513

High

376515

CKLF
Chemokine-like factor

1

0

High-throughput

0.513

High

376518

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.513

High

376519

SC5A6
Sodium-dependent multivitamin transporter

1

0

High-throughput

0.513

High

270251

LRP6
Low-density lipoprotein receptor-related protein 6

1

2

Small-scale

0.501

High

376410

HS90A
Heat shock protein HSP 90-alpha

1

1

Small-scale

0.501

High

376412

LIPC
Hepatic triacylglycerol lipase

1

3

Small-scale

0.501

High

326846

FADS2
Acyl-CoA 6-desaturase

1

0

High-throughput

0.493

High

376460

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

0

High-throughput

0.493

High

376417

CD36
Platelet glycoprotein 4

1

0

Small-scale

0.480

High

376422

PGS1
Biglycan

1

0

Small-scale

0.480

High

376452

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.480

High

376514

TREM2
Triggering receptor expressed on myeloid cells 2

1

0

Small-scale

0.480

High

119072

LEG9
Galectin-9

1

1

Small-scale

0.479

High

148268

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

345653

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

349054

RASH
GTPase HRas

1

1

High-throughput

0.479

High

376405

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

376414

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

376416

ENPL
Endoplasmin

1

1

Small-scale

0.479

High

376419

LEG3
Galectin-3

1

1

Small-scale

0.479

High

376420

VGFR1
Vascular endothelial growth factor receptor 1

1

1

High-throughput

0.479

High

376427

CALR
Calreticulin

1

1

Small-scale

0.479

High

376433

TRI23
E3 ubiquitin-protein ligase TRIM23

1

2

High-throughput

0.479

High

376434

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

1

High-throughput

0.479

High

376437

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

376441

VMAT1
Chromaffin granule amine transporter

1

2

High-throughput

0.479

High

376446

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

2

Small-scale

0.479

High

376462

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

376464

P2Y14
P2Y purinoceptor 14

1

2

High-throughput

0.479

High

376468

TGO1
Transport and Golgi organization protein 1 homolog

1

1

Small-scale

0.479

High

376509

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

376430

AKT2
RAC-beta serine/threonine-protein kinase

1

0

High-throughput

0.460

High

376451

SMAD3
Mothers against decapentaplegic homolog 3

1

0

High-throughput

0.460

High

376458

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.460

High

376485

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.460

High

373486

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

376409

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

376418

CXA1
Gap junction alpha-1 protein

1

0

Small-scale

0.458

High

376423

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

Small-scale

0.458

High

376426

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

376429

CALCR
Calcitonin receptor

1

0

Small-scale

0.458

High

376439

CTCF
Transcriptional repressor CTCF

1

0

Small-scale

0.458

High

376444

MLF1
Myeloid leukemia factor 1

1

0

High-throughput

0.458

High

376445

SC61B
Protein transport protein Sec61 subunit beta

1

0

Small-scale

0.458

High

376448

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

376449

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

376450

YBOX1
Y-box-binding protein 1

1

0

Small-scale

0.458

High

376456

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

376459

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

376461

CUL7
Cullin-7

1

0

High-throughput

0.458

High

376481

S38A6
Solute carrier family 38 member 6

1

0

High-throughput

0.458

High

376492

PLIN2
Perilipin-2

1

0

Small-scale

0.458

High

376498

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

376499

TRIM6
Tripartite motif-containing protein 6

1

0

Small-scale

0.458

High

376500

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

376503

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

376516

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

376522

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

0

Small-scale

0.458

High

376472

LMTK1
Serine/threonine-protein kinase LMTK1

1

1

High-throughput

0.457

High

376431

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

260451

PITX3
Pituitary homeobox 3

1

2

Small-scale

0.437

High

376474

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.437

High

376479

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.437

High

376497

YIPF2
Protein YIPF2

1

1

High-throughput

0.437

High

376501

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.437

High

376407

IPSP
Plasma serine protease inhibitor

1

0

Small-scale

0.426

High

376408

PRGR
Progesterone receptor

1

0

Small-scale

0.426

High

376447

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.426

High

376483

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

376491

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

81597

B7Z3K1
cDNA FLJ51973

1

1

High-throughput

0.407

High

49399

TMM72
Transmembrane protein 72

1

0

High-throughput

0.279

Low

376470

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

0

High-throughput

0.279

Low

376471

STUM
Protein stum homolog

1

0

High-throughput

0.279

Low

376478

S22A9
Organic anion transporter 7

1

0

High-throughput

0.279

Low

376482

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

376484

KTAP2
Keratinocyte-associated protein 2

1

0

High-throughput

0.279

Low

376486

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.279

Low

376510

KISHB
Protein kish-B

1

0

High-throughput

0.279

Low

376517

PHF11
PHD finger protein 11

1

0

High-throughput

0.279

Low

376521

T184B
Transmembrane protein 184B

1

0

High-throughput

0.279

Low

215780

B3GT2
Beta-1,3-galactosyltransferase 2

1

0

High-throughput

0.249

Low

308306

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.249

Low

328694

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

376463

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.249

Low

376480

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

376520

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024